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- Title
Surgical management of recurrent sinonasal mucosal melanoma: endoscopic or transfacial resection.
- Authors
Ledderose, G.; Leunig, A.
- Abstract
Sinonasal mucosal melanoma (SNMM) is associated with poor prognosis. Local recurrence is common and represents a major problem in the therapy. Wide resection surgery is usually applied. However, given the almost futile prognosis, optimal symptom control may be preferable to wide resection at all costs. The aim of our study was to analyze the outcome in patients with recurrent SNMM treated by transfacial radical surgery or by a less invasive endoscopically controlled approach. Patients with recurrent grade III or IV staged SNMM who presented to our ENT department between 2000 and 2010 were either treated by transfacial ( n = 10) or endoscopically controlled surgery ( n = 12). The patients' charts were reviewed for clinical symptoms, relapse-free time and survival time. Clinical symptoms improved after surgery. The morbidity after endoscopic surgery was significantly lower than after transfacial surgery. The chosen surgical technique did neither affect relapse-free nor survival time. When treating recurrent SNMM, the comparatively gentle and less mutilating endoscopic approach proved to be a sufficient surgical procedure, being not inferior to aggressive surgery with respect to recurrence and survival rate.
- Subjects
MUCOUS membrane cancer; CANCER relapse; DISEASE management; SURGICAL complications; SURVIVAL analysis (Biometry)
- Publication
European Archives of Oto-Rhino-Laryngology, 2015, Vol 272, Issue 2, p351
- ISSN
0937-4477
- Publication type
Article
- DOI
10.1007/s00405-014-3119-y