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- Title
Pathways of clathrin-independent endocytosis.
- Authors
Mayor, Satyajit; Pagano, Richard E.
- Abstract
There are numerous ways that endocytic cargo molecules may be internalized from the surface of eukaryotic cells. In addition to the classical clathrin-dependent mechanism of endocytosis, several pathways that do not use a clathrin coat are emerging. These pathways transport a diverse array of cargoes and are sometimes hijacked by bacteria and viruses to gain access to the host cell. Here, we review our current understanding of various clathrin-independent mechanisms of endocytosis and propose a classification scheme to help organize the data in this complex and evolving field.
- Subjects
ENDOCYTOSIS; MOLECULAR biology; PROTEINS; CELLULAR mechanics; DROSOPHILA melanogaster; CYTOLOGY
- Publication
Nature Reviews Molecular Cell Biology, 2007, Vol 8, Issue 8, p603
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm2216