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- Title
New potential solutions for the chemolysis of urinary phosphate calculi determined by an in vitro study.
- Authors
Zhang, Jinqing; Wang, Shuo; Hong, Jingfan; Liu, Chunxiao; Jiang, Yanbin
- Abstract
To find a more efficient solution for chemolysis of urinary calculi, several organic acids were chosen to form solutions by consulting the composition of a classic solution, Suby G. The solutions together with Renacidin, another classic solution, were designed to react with the 4 phosphate components of urinary stone. The processes were real-time measured and analysed by a focused beam reflectance measurement, and the efficiency factors were investigated and discussed in detail. The results show that several organic acids, e.g. hydroxyacetic acid, lactic acid and α-ketoglutaric acid, are more efficient than citric acid in dissolving urinary phosphate calculus. The new solutions containing the organic acids are promising for improving chemolysis treatment.
- Subjects
URINARY calculi; ORGANIC acids; CALCIUM phosphate; IN vitro studies; GLYCOLIC acid; REFLECTANCE measurement; THERAPEUTICS
- Publication
Urolithiasis, 2015, Vol 43, Issue 2, p147
- ISSN
2194-7228
- Publication type
Article
- DOI
10.1007/s00240-014-0745-1