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- Title
Occurrence and risk factors for benign epithelial gastric polyps in atrophic body gastritis on diagnosis and follow-up.
- Authors
Di Giulio, E.; Lahner, E.; Micheletti, A.; Milione, M.; D'Ambra, G.; Bordi, C.; Delle Fave, G.; Annibale, B.
- Abstract
: Benign epithelial gastric polyps have been reported to be more common in atrophic body gastritis. The role ofHelicobacter pyloriinfection in the induction of gastric atrophy is well-known. The development of hyperplastic polyps may be in relation toH. pyloriinfection.: To investigate occurrence of benign epithelial gastric polyps in atrophic body gastritis patients at diagnosis and follow-up, and the role ofH. pyloriand other risk factors for the development of benign epithelial gastric polyps.: A total of 259 consecutive atrophic body gastritis patients included in a follow-up programme, of whom 202 were followed up for median period of 4 years (range: 2–11). At baseline and follow-up gastroscopies, the presence of benign epithelial gastric polyps was evaluated. Biopsies for histology were obtained from all detected benign epithelial gastric polyps.: Frequency of benign epithelial gastric polyps in atrophic body gastritis patients were 4.6% at baseline and 5.9% at follow-up. About 91.7% were hyperplastic polyps.H. pyloriinfection was detected in 79.2% atrophic body gastritis patients with benign epithelial gastric polyps, and in 70.8% without benign epithelial gastric polyps. Smoking was more frequent among patients with benign epithelial gastric polyps [42% vs. 20%, OR 2.8 (95% CI: 1.2–6.9)].: Benign epithelial gastric polyps occur in about 5% of atrophic body gastritis patients, and the vast majority are hyperplastic polyps. Smoking habit, but notH. pyloriinfection, increases the risk for benign epithelial gastric polyps in atrophic body gastritis patients.
- Subjects
GASTRITIS; POLYPS; DISEASE risk factors; DIAGNOSIS; CLINICAL pathology; HISTOPATHOLOGY
- Publication
Alimentary Pharmacology & Therapeutics, 2005, Vol 21, Issue 5, p567
- ISSN
0269-2813
- Publication type
Article
- DOI
10.1111/j.1365-2036.2005.02399.x