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- Title
Roles of microRNAs in the Hepatitis B Virus Infection and Related Diseases.
- Authors
Muriel Thirion; Takahiro Ochiya
- Abstract
The hepatitis B virus (HBV) is a small enveloped DNA virus that belongs to the Hepadnaviridae family. HBV can cause acute and persistent infection which can lead to hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play a crucial role in the main cellular events. The dysregulation of their expression has been linked to the development of the cancer as well as to viral interference. This chapter will describe the involvement of miRNAs in the case of HBV infection and their implication in the development of the HBV-related diseases.
- Subjects
HEPATITIS B virus; HEPATITIS associated antigen; MICRORNA genetics; IMMUNE system; ANTIBODY formation; COMMUNICABLE diseases; LIVER cancer
- Publication
Viruses (1999-4915), 2013, Vol 5, Issue 11, p2690
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v5112690