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In Silico, In Vitro, and In Vivo Investigations on Adapalene as Repurposed Third Generation Retinoid against Multiple Myeloma and Leukemia.
Published in:
Cancers, 2023, v. 15, n. 16, p. 4136, doi. 10.3390/cancers15164136
By:
- Boulos, Joelle C.;
- Chatterjee, Manik;
- Shan, Letian;
- Efferth, Thomas
Publication type:
Article
Targeting polo-like kinase 1 suppresses essential functions of alloreactive T cells.
Published in:
Immunologic Research, 2016, v. 64, n. 3, p. 687, doi. 10.1007/s12026-015-8778-2
By:
- Berges, Carsten;
- Chatterjee, Manik;
- Topp, Max;
- Einsele, Hermann
Publication type:
Article
The heat shock protein 70 inhibitor VER155008 suppresses the expression of HSP27, HOP and HSP90β and the androgen receptor, induces apoptosis, and attenuates prostate cancer cell growth.
Published in:
Journal of Cellular Biochemistry, 2020, v. 121, n. 1, p. 407, doi. 10.1002/jcb.29195
By:
- Brünnert, Daniela;
- Langer, Clara;
- Zimmermann, Luise;
- Bargou, Ralf C.;
- Burchardt, Martin;
- Chatterjee, Manik;
- Stope, Matthias B.
Publication type:
Article
OAB-017: Attenuation of T cell cytotoxicity mediated by CD200 expression on multiple myeloma cells.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S11, doi. 10.1016/S2152-2650(21)02091-7
By:
- Shah, Pooja;
- Stühmer, Thorsten;
- Brünnert, Daniela;
- Munawar, Umair;
- Leich, Ellen;
- Kraus, Sabrina;
- Chatterjee, Manik;
- Schlosser, Andreas;
- Bargou, Ralf C.;
- Einsele, Hermann;
- Berberich-Siebelt, Friederike;
- Steinbrunn, Torsten
Publication type:
Article
Functional characterization of the RAL-dependent survival pathway in multiple myeloma.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e138, doi. 10.1016/j.clml.2019.09.230
By:
- Seibold, Marcel;
- Stühmer, Thorsten;
- Mottok, Anja;
- Scholz, Claus;
- Chatterjee, Manik;
- Leich, Ellen;
- Barrio, Santiago;
- Kortüm, K.M.;
- Schlosser, Andreas;
- Rosenwald, Andreas;
- Einsele, Hermann;
- Bargou, Ralf C.;
- Steinbrunn, Torsten
Publication type:
Article
CD200 expressing multiple myeloma cells show increased resistance against T cell-mediated cytotoxicity.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e138, doi. 10.1016/j.clml.2019.09.229
By:
- Shah, Pooja;
- Stühmer, Thorsten;
- Brünnert, Daniela;
- Munawar, Umair;
- Chatterjee, Manik;
- Hudecek, Michael;
- Einsele, Hermann;
- Berberich-Siebelt, Friederike;
- Bargou, Ralf C.;
- Steinbrunn, Torsten
Publication type:
Article
A Phase 1, First-in-Human Study of AMG 176, a Selective MCL-1 Inhibitor, in Patients With Relapsed or Refractory Multiple Myeloma.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e53, doi. 10.1016/j.clml.2019.09.081
By:
- Spencer, Andrew;
- Rosenberg, Aaron Seth;
- Jakubowiak, Andrzej;
- Raje, Noopur;
- Chatterjee, Manik;
- Trudel, Suzanne;
- Bahlis, Nizar J.;
- Siegel, David S.;
- Wilop, Stefan;
- Harrison, Simon J.;
- NagaKrishna, Murthy;
- Dhuria, Shyeilla;
- Hindoyan, Antreas;
- McIver, Zach;
- Henary, Haby;
- Morrow, Phuong Khanh;
- Roberts, Andrew
Publication type:
Article
A phase I/IIa Study of the CD38 Antibody MOR202 in Combination With Pomalidomide or Lenalidomide in Patients With Relapsed or Refractory Multiple Myeloma.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. e61, doi. 10.1016/j.clml.2017.03.112
By:
- Chatterjee, Manik;
- Raab, Marc S.;
- Goldschmidt, Hartmut;
- Agis, Hermine;
- Blau, Igor Wolfgang;
- Einsele, Hermann;
- Engelhardt, Monika;
- Ferstl, Barbara;
- Günther, Andreas;
- Röllig, Christoph;
- Weisel, Katja;
- Jarutat, Tiantom;
- Weinelt, Dominika;
- Winderlich, Mark;
- Boxhammer, Rainer;
- Peschel, Christian
Publication type:
Article
RalA and RalB are Potential Therapeutic Targets in Multiple Myeloma Which Mediate Cell Survival Independently of Oncogenic RAS.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. e110, doi. 10.1016/j.clml.2017.03.200
By:
- Steinbrunn, Torsten;
- Seibold, Marcel;
- Stühmer, Thorsten;
- Schmiedl, Nadine;
- Mottok, Anja;
- Leich, Ellen;
- Scholz, Claus;
- Chatterjee, Manik;
- Rosenwald, Andreas;
- Einsele, Hermann;
- Bargou, Ralf C.
Publication type:
Article
Novel molecular subgroups within the context of receptor tyrosine kinase and adhesion signalling in multiple myeloma.
Published in:
2021
By:
- Leich, Ellen;
- Schreder, Martin;
- Pischimarov, Jordan;
- Stühmer, Thorsten;
- Steinbrunn, Torsten;
- Rudelius, Martina;
- Brünnert, Daniela;
- Chatterjee, Manik;
- Langer, Christian;
- Keppler, Sarah;
- Heredia-Guerrero, Sofia Catalina;
- Einsele, Hermann;
- Knop, Stefan;
- Bargou, Ralf Christian;
- Rosenwald, Andreas
Publication type:
Letter to the Editor
Neue Formen der Immuntherapie für die Uroonkologie: HLA-unabhängige Therapieansätze mit bispezifischen Antikörpern und CAR-T-Zellen.
Published in:
Die Urologie, 2023, v. 62, n. 7, p. 685, doi. 10.1007/s00120-023-02117-1
By:
- Krebs, Markus;
- Chatterjee, Manik;
- Kübler, Hubert;
- Kalogirou, Charis
Publication type:
Article
CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma.
Published in:
British Journal of Haematology, 2017, v. 179, n. 1, p. 36, doi. 10.1111/bjh.14807
By:
- Waldschmidt, Johannes M.;
- Simon, Anna;
- Wider, Dagmar;
- Müller, Stefan J.;
- Follo, Marie;
- Ihorst, Gabriele;
- Decker, Sarah;
- Lorenz, Joschka;
- Chatterjee, Manik;
- Azab, Abdel K.;
- Duyster, Justus;
- Wäsch, Ralph;
- Engelhardt, Monika
Publication type:
Article
From CLL to Multiple Myeloma - Spleen Tyrosine Kinase ( SYK) influences multiple myeloma cell survival and migration.
Published in:
British Journal of Haematology, 2016, v. 174, n. 6, p. 985, doi. 10.1111/bjh.13825
By:
- Lorenz, Joschka;
- Waldschmidt, Johannes;
- Wider, Dagmar;
- Follo, Marie;
- Ihorst, Gabriele;
- Chatterjee, Manik;
- May, Annette M.;
- Duyster, Justus;
- Rosenwald, Andreas;
- Wäsch, Ralph;
- Zirlik, Katja;
- Engelhardt, Monika
Publication type:
Article
PI3K-dependent multiple myeloma cell survival is mediated by the PIK3 CA isoform.
Published in:
British Journal of Haematology, 2014, v. 166, n. 4, p. 529, doi. 10.1111/bjh.12920
By:
- Hofmann, Claudia;
- Stühmer, Thorsten;
- Schmiedl, Nadine;
- Wetzker, Reinhard;
- Mottok, Anja;
- Rosenwald, Andreas;
- Langer, Christian;
- Zovko, Josip;
- Chatterjee, Manik;
- Einsele, Hermann;
- Bargou, Ralf C.;
- Steinbrunn, Torsten
Publication type:
Article
The heat shock transcription factor 1 as a potential new therapeutic target in multiple myeloma.
Published in:
British Journal of Haematology, 2013, v. 160, n. 4, p. 465, doi. 10.1111/bjh.12164
By:
- Heimberger, Tanja;
- Andrulis, Mindaugas;
- Riedel, Simone;
- Stühmer, Thorsten;
- Schraud, Heike;
- Beilhack, Andreas;
- Bumm, Thomas;
- Bogen, Bjarne;
- Einsele, Hermann;
- Bargou, Ralf C.;
- Chatterjee, Manik
Publication type:
Article
Combined targeting of MEK/ MAPK and PI3 K/ Akt signalling in multiple myeloma.
Published in:
British Journal of Haematology, 2012, v. 159, n. 4, p. 430, doi. 10.1111/bjh.12039
By:
- Steinbrunn, Torsten;
- Stühmer, Thorsten;
- Sayehli, Cyrus;
- Chatterjee, Manik;
- Einsele, Hermann;
- Bargou, Ralf C.
Publication type:
Article
Disruption of Lipid Raft Microdomains, Regulation of CD38, TP53, and MYC Signaling, and Induction of Apoptosis by Lomitapide in Multiple Myeloma Cells.
Published in:
Cancer Genomics & Proteomics (1109-6535), 2022, v. 19, n. 5, p. 540, doi. 10.21873/cgp.20339
By:
- SAEED, MOHAMED E. M.;
- BOULOS, JOELLE C.;
- MÜCKLICH, SABRINA B.;
- LEICH, ELLEN;
- CHATTERJEE, MANIK;
- KLAUCK, SABINE M.;
- EFFERTH, THOMAS
Publication type:
Article
Efficient Transient Transfection of Human Multiple Myeloma Cells by Electroporation – An Appraisal.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0097443
By:
- Steinbrunn, Torsten;
- Chatterjee, Manik;
- Bargou, Ralf C.;
- Stühmer, Thorsten
Publication type:
Article
The Natural Human IgM Antibody PAT-SM6 Induces Apoptosis in Primary Human Multiple Myeloma Cells by Targeting Heat Shock Protein GRP78
Published in:
PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063414
By:
- Rasche, Leo;
- Duell, Johannes;
- Morgner, Charlotte;
- Chatterjee, Manik;
- Hensel, Frank;
- Rosenwald, Andreas;
- Einsele, Hermann;
- Topp, Max S.;
- Brändlein, Stephanie
Publication type:
Article
Targeting of the E3 ubiquitin-protein ligase HUWE1 impairs DNA repair capacity and tumor growth in preclinical multiple myeloma models.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75499-3
By:
- Kunz, Viktoria;
- Bommert, Kathryn S.;
- Kruk, Jessica;
- Schwinning, Daniel;
- Chatterjee, Manik;
- Stühmer, Thorsten;
- Bargou, Ralf;
- Bommert, Kurt
Publication type:
Article
The IL-6 receptor antagonist SANT-7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells.
Published in:
International Journal of Cancer, 2001, v. 93, n. 5, p. 674, doi. 10.1002/ijc.1388
By:
- Hönemann, Dirk;
- Chatterjee, Manik;
- Savino, Rocco;
- Bommert, Kurt;
- Burger, Renate;
- Gramatzki, Martin;
- Dörken, Bernd;
- Bargou, Ralf C.
Publication type:
Article
Ancistrocladinium A Induces Apoptosis in Proteasome Inhibitor-Resistant Multiple Myeloma Cells: A Promising Therapeutic Agent Candidate.
Published in:
Pharmaceuticals (14248247), 2023, v. 16, n. 8, p. 1181, doi. 10.3390/ph16081181
By:
- Brünnert, Daniela;
- Seupel, Raina;
- Goyal, Pankaj;
- Bach, Matthias;
- Schraud, Heike;
- Kirner, Stefanie;
- Köster, Eva;
- Feineis, Doris;
- Bargou, Ralf C.;
- Schlosser, Andreas;
- Bringmann, Gerhard;
- Chatterjee, Manik
Publication type:
Article
Repurposing of the ALK Inhibitor Crizotinib for Acute Leukemia and Multiple Myeloma Cells.
Published in:
Pharmaceuticals (14248247), 2021, v. 14, n. 11, p. 1126, doi. 10.3390/ph14111126
By:
- Boulos, Joelle C.;
- Saeed, Mohamed E. M.;
- Chatterjee, Manik;
- Bülbül, Yagmur;
- Crudo, Francesco;
- Marko, Doris;
- Munder, Markus;
- Klauck, Sabine M.;
- Efferth, Thomas
Publication type:
Article
Preclinical anti-myeloma activity of the novel HDAC-inhibitor JNJ-26481585.
Published in:
British Journal of Haematology, 2010, v. 149, n. 4, p. 529, doi. 10.1111/j.1365-2141.2010.08126.x
By:
- Stühmer, Thorsten;
- Arts, Janine;
- Chatterjee, Manik;
- Borawski, Johanna;
- Wolff, André;
- King, Peter;
- Einsele, Hermann;
- Leo, Eugen;
- Bargou, Ralf C.
Publication type:
Article
Anti-myeloma activity of the novel 2-aminothienopyrimidine Hsp90 inhibitor NVP-BEP800.
Published in:
British Journal of Haematology, 2009, v. 147, n. 3, p. 319, doi. 10.1111/j.1365-2141.2009.07852.x
By:
- Stühmer, Thorsten;
- Chatterjee, Manik;
- Grella, Evelyn;
- Seggewiss, Ruth;
- Langer, Christian;
- Müller, Sabine;
- Schoepfer, Joseph;
- Garcia-Echeverria, Carlos;
- Quadt, Cornelia;
- Jensen, Michael R.;
- Einsele, Hermann;
- Bargou, Ralf C.
Publication type:
Article

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