We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Complications of the endovascular management of acute ischemic stroke.
- Authors
Gill, Heather L.; Siracuse, Jeffrey J.; Parrack, In-Kyong; Huang, Zhen S.; Meltzer, Andrew J.
- Abstract
Acute ischemic stroke is a significant source of morbidity and mortality across the globe. Currently, the only US Food and Drug Administration approved medical treatment of acute ischemic stroke is intravascular (IV) alteplase. While IV thrombolysis has been shown to decrease morbidity and mortality from acute ischemic stroke, it is limited in both its efficacy in certain types of stroke, as well as in its generalizability. It has been shown that time to revascularization is one of the most important predictors of outcomes in acute ischemic stroke, and thus clinicians have turned to endovascular options in efforts to improve outcomes from stroke. Direct intra-arterial thrombolysis was one of the first of such efforts to improve efficacy rates and increase the timeline for thrombolytic therapy. More recently, investigators and clinicians have turned to newer endovascular options in attempts to further improve recanalization rates. Many different endovascular techniques have been employed and are growing exponentially in use. Examples include stenting, as well as mechanical thrombectomy with both older-generation devices and newer stent retrieval technology. While the majority of the literature focuses on the effectiveness of different techniques, such as recanalization rates and major overall outcomes such as death and disability, there is very little literature on the complications of the different techniques. The purpose of this article is to review the different forms of endovascular treatment of acute ischemic stroke and their associated complications.
- Subjects
CORONARY heart disease treatment; DISEASE complications; DISEASE management; HEALTH outcome assessment; UNITED States. Food &; Drug Administration
- Publication
Vascular Health & Risk Management, 2014, Vol 10, p675
- ISSN
1176-6344
- Publication type
Article
- DOI
10.2147/VHRM.S44349