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- Title
Partial hydatidiform mole in a pregnant chimpanzee ( Pan troglodytes).
- Authors
Debyser, Isolde W. J.; Soma, Hiroaki; Zwart, Peernel
- Abstract
Until now, the occurrence of hydatidiform mole in non-human primates has not been documented. This report presents a case in which a stillborn fetus, associated with a partial hydatidiform mole, was found at necropsy in the uterus of a pregnant chimpanzee ( Pan troglodytes) which had suddenly died. Hydropic swelling of the chorionic villi and proliferation of trophoblastic cells were present. The trophoblast was stained enzyme-immunohistochemically with human chorionic gonadotropin (hCG) and pregnancy-specific-β1-glycoprotein (SP1). The concentrations of hCG and SP1 in maternal serum were high, 1,350 mIU/ml and 1,000 ng/ml, respectively. The distribution of DNA content of the cytotrophoblast in the molar villi shifted from diploid to an aneuploid pattern. © 1993 Wiley-Liss, Inc.
- Publication
Zoo Biology, 1993, Vol 12, Issue 3, p299
- ISSN
0733-3188
- Publication type
Article
- DOI
10.1002/zoo.1430120307