We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Modifiable Risk Factors for Pneumonia Requiring Hospitalization of Community-Dwelling Older Adults: The Health, Aging, and Body Composition Study.
- Authors
Juthani‐Mehta, Manisha; De Rekeneire, Nathalie; Allore, Heather; Chen, Shu; O'Leary, John R.; Bauer, Douglas C.; Harris, Tamara B.; Newman, Anne B.; Yende, Sachin; Weyant, Robert J.; Kritchevsky, Stephen; Quagliarello, Vincent
- Abstract
Objectives To identify novel modifiable risk factors, focusing on oral hygiene, for pneumonia requiring hospitalization of community-dwelling older adults. Design Prospective observational cohort study. Setting Memphis, Tennessee, and Pittsburgh, Pennsylvania. Participants Of 3,075 well-functioning community-dwelling adults aged 70 to 79 enrolled in the Health, Aging, and Body Composition Study from 1997 to 1998, 1,441 had complete data in the data set of all variables used, a dental examination within 6 months of baseline, and were eligible for this study. Measurements The primary outcome was pneumonia requiring hospitalization through 2008. Results Of 1,441 participants, 193 were hospitalized for pneumonia. In a multivariable model, male sex (hazard ratio ( HR) = 2.07, 95% confidence interval ( CI) = 1.51-2.83), white race ( HR = 1.44, 95% CI = 1.03-2.01), history of pneumonia ( HR = 3.09, 95% CI = 1.86-5.14), pack-years of smoking ( HR = 1.006, 95% CI = 1.001-1.011), and percentage of predicted forced expiratory volume in 1 minute (moderate vs mild lung disease or normal lung function, HR = 1.78, 95% CI = 1.28-2.48; severe lung disease vs mild lung disease or normal lung function, HR = 2.90, 95% CI = 1.51-5.57) were nonmodifiable risk factors for pneumonia. Incident mobility limitation ( HR = 1.77, 95% CI = 1.32-2.38) and higher mean oral plaque score ( HR = 1.29, 95% CI = 1.02-1.64) were modifiable risk factors for pneumonia. Average attributable fractions revealed that 11.5% of cases of pneumonia were attributed to incident mobility limitation and 10.3% to a mean oral plaque score of 1 or greater. Conclusion Incident mobility limitation and higher mean oral plaque score were two modifiable risk factors that 22% of pneumonia requiring hospitalization could be attributed to. These data suggest innovative opportunities for pneumonia prevention among community-dwelling older adults.
- Subjects
PENNSYLVANIA; TENNESSEE; RISK factors of pneumonia; AGING; BODY composition; CONFIDENCE intervals; HOSPITAL care; LONGITUDINAL method; SCIENTIFIC observation; RESEARCH funding; STATISTICS; TOOTH care &; hygiene; INDEPENDENT living; PROPORTIONAL hazards models; DATA analysis software; DESCRIPTIVE statistics; OLD age
- Publication
Journal of the American Geriatrics Society, 2013, Vol 61, Issue 7, p1111
- ISSN
0002-8614
- Publication type
Article
- DOI
10.1111/jgs.12325