We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Ten‐year single‐centre experience in fertility preservation of 459 patients suffering from acute leukaemia.
- Authors
Noetzli, Jasmine; Voruz, Sophie; Wunder, Dorothea; Primi, Marie‐Pierre; Spertini, Olivier; Blum, Sabine
- Abstract
Summary: Acute leukaemia is a life‐threatening disease that needs treatment without delay. Fertility preservation is recommended, but often not possible because of the necessity to start treatment as soon as possible. The present study is a retrospective single‐centre analysis of 459 patients diagnosed with acute leukaemia between 2002 and 2012. Sperm or oocyte preservation was successfully performed in only 29 (6%) patients. Of the 150 children, no paediatric patient sample was taken. The collected samples enabled the conception of 2 children by in vitro fertilisation; in addition, 3 spontaneous, non‐assisted births in partners of male patients were observed. Fertility preservation is important but difficult to accomplish in patients with acute leukaemia; more efforts are clearly needed to preserve fertility in long‐term survivors of acute leukaemia.
- Subjects
FERTILITY preservation
- Publication
British Journal of Haematology, 2019, Vol 184, Issue 6, p969
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.15740