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- Title
Dose-Adjusted EPOCH-R and Mid-Cycle High Dose Methotrexate for Patients with Systemic Lymphoma and secondary CNS Involvement.
- Authors
Chihara, Dai; Fowler, Nathan H.; Oki, Yasuhiro; Fanale, Michelle A.; Fayad, Luis E.; Westin, Jason R.; Hagemeister, Fredrick B.
- Abstract
The article discusses the treatment of patients with systemic lymphoma who have secondary central nervous system (CNS) involvement using dose-adjusted etoposide, prednisone, vincristine/Oncovin and doxorubicin hydrochloride in combination with rituximab (EPOCH-R) and mid-cycle high dose methotrexate. Topics discussed include survival outcome, complete response (CR) achieved by all patients, and the relapse-free status of patients who did not undergo autologous stem cell transplantation (ASCT).
- Subjects
LYMPHOMA treatment; ETOPOSIDE; PREDNISONE; VINCRISTINE; DOXORUBICIN; RITUXIMAB; METHOTREXATE; DRUG dosage
- Publication
British Journal of Haematology, 2017, Vol 179, Issue 5, p851
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.14267