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- Title
Prognostic value of histopathological parameters in 51 supraglottic squamous cell carcinomas.
- Authors
De Guzmán, R. Barona; Martorell, M. A.; Basterra, J.; Armengot, M.; Alvarez-Valdés, R.; Garin, L.
- Abstract
The prognosis for supraglottic squamous cell carcinomas is difficult to establish. A study of 19 histopathological parameters (14 from the primary tumor and 5 from the lymph node metastases) was undertaken in 51 supraglottic epidermoid carcinomas. All patients were subjected to supraglottic horizontal laryngectomy with bilateral functional neck dissection and postoperative radiotherapy. A discriminant analysis was performed to relate the different histopathological variables to 5-year survival. Capsule rupture and the number of metastatic lymph nodes were the only two parameters significantly related to survival ( P <.01). Histopathology (in particular, lymph node metastases) proved more effective in predicting patient evolution than TNM staging.
- Publication
Laryngoscope, 1993, Vol 103, Issue 5, p538
- ISSN
0023-852X
- Publication type
Article
- DOI
10.1288/00005537-199305000-00011