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- Title
Multiple intracranial and spinal metastases from a nonfunctioning pituitary adenoma following multiple surgeries: an illustrative case with 16 years of follow-up.
- Authors
Jun Wang; Er-meng Ma; Peng-fei Wu; Bo Qiu; Yun-jie Wang
- Abstract
Pituitary adenomas are the third most common primary intracranial tumor; however, those with postoperative metastases are very rare and are classically considered as pituitary carcinomas. The field of neurosurgery has struggled with diagnosing and treating these unusual lesions. In this report, we retrospectively analyze the clinical features, imaging findings, pathological characteristics and prognosis of one patient with non-hormonesecreting pituitary adenoma who had multiple intracranial and spinal metastases and underwent four surgeries in a 16-year follow-up period. In addition, on the basis of the existing literature, we explore the underlying mechanisms of, as well as the preventive and therapeutic strategies used to treat, pituitary carcinomas and postoperative metastasis of pituitary tumors.
- Subjects
INTRACRANIAL tumors; PITUITARY tumors; MICROSURGERY; ADENOMA
- Publication
World Journal of Surgical Oncology, 2014, Vol 12, Issue 1, p131
- ISSN
1477-7819
- Publication type
Case Study
- DOI
10.1186/1477-7819-12-380