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- Title
Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36.
- Authors
Butler, Jill S; Dent, Sharon Y R
- Abstract
The article focuses on the studies by Venkatest and colleagues and Smolle and colleagues regarding the regulation of genes. It mentions that nuclesomes hampered the movement and recruitment of RNA polymerase II (RNAPII) and the association of transcription machinery. It states that histone and differential acetylation of newly incorporated and pre-existing histones regulate the replacement and eviction of nucleosomal histones during transcription elongation.
- Subjects
GENETIC regulation; METHYLATION; HISTONES; ELONGATION factors (Biochemistry); RNA polymerases
- Publication
Nature Structural & Molecular Biology, 2012, Vol 19, Issue 9, p863
- ISSN
1545-9993
- Publication type
Article
- DOI
10.1038/nsmb.2370