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- Title
Anti-oesophageal cancer activity in extracts of deep-water Marion Island sponges.
- Authors
Davies-Coleman, Michael T.; Froneman, William; Keyzers, Robert A.; Whibley, Catherine; Hendricks, Denver; Samaai, Toufiek; McQuaid, Christopher
- Abstract
Oesophageal cancer is one of the most common causes of cancer-related deaths in South African black males. The limited efficacy of chemotherapeutic agents to treat this disease has prompted a search for potential new chemical entities with anti-cancer properties. We report here on the evidence for anti-oesophageal cancer activity in the methanolic extracts of five species of sponges dredged from a depth of approximately 100 m in the vicinity of Marion Island in the Southern Ocean during the autumn of 2004.
- Subjects
MARION Island (Prince Edward Islands); SOUTH Africa; ANTINEOPLASTIC agents; SPONGES (Invertebrates); CANCER treatment; SOUTH African Journal of Science (Periodical); DISEASES; BLACK people; MALES; THERAPEUTICS
- Publication
South African Journal of Science, 2005, Vol 101, Issue 11/12, p489
- ISSN
0038-2353
- Publication type
Article