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- Title
Clinical characteristics of moderate COVID‐19 patients aggravation in Wuhan Stadium Cabin Hospital: A 571 cases of retrospective cohort study.
- Authors
Shu, Lei; Wang, Xiaoyan; Li, Mingquan; Chen, Xiaolin; Ji, Ningfei; Shi, Lei; Wu, Mingjing; Deng, Kaili; Wei, Jing; Wang, Xueli; Cao, Yang; Yan, Jiaxin; Feng, Ganzhu
- Abstract
To report the clinical characteristics and potential risk factors of patients with coronavirus disease 2019 (COVID‐19) in Wuhan Stadium Cabin Hospital in Hubei Province. A total of 571 patients of COVID‐19 treated in the Wuhan Stadium Cabin Hospital were selected for analysis, univariable and multivariable logistic regression methods were used to explore the risk factors associated with disease aggravation. The main clinical symptoms of moderate COVID‐19 were fever, cough and dyspnea, hypertension, diabetes, and coronary heart diseases were the main comorbidities both in transferred and stable patients. Twenty‐six patients (4.55%) of mild and moderate patients had disease aggravation, and most of which occurred between 36 and 48 hours after admission. Multiple regression analysis showed increasing odds of disease aggravation associated with former smoker history, diabetes, dyspnea, consolidation, and interstitial abnormalities of computed tomography scanning, lymphopenia and elevated of C‐reactive protein, the time points of transferred patients mainly between 36 and 48 hours (65.38%), and the average hospital stay for stable patients was 15 days.It could help clinicians to identify patients with poor prognosis at an early stage, and provide early warning role for timely intervention. Highlights: The main clinical symptoms of moderate COVID‐19 were fever, cough and dyspnea.Hypertension, diabetes and coronary heart diseases were the main comorbidities both in transferred and stable patients.4.55% of mild and moderate patients had disease aggravation, and most of which occurred between 36 hours to 48 hours after admission.Increasing odds of disease aggravation associated with former smoker history, diabetes, dyspnea, consolidation and interstitial abnormalities of CT scanning, lymphopenia and elevated of CRP.
- Subjects
HUBEI Sheng (China); COVID-19; COMPUTED tomography; MULTIPLE regression analysis; DISEASE risk factors; CORONARY disease; LYMPHOPENIA
- Publication
Journal of Medical Virology, 2021, Vol 93, Issue 2, p1133
- ISSN
0146-6615
- Publication type
Article
- DOI
10.1002/jmv.26414