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- Title
The lenalidomide/bortezomib/dexamethasone regimen for the treatment of blastic plasmacytoid dendritic cell neoplasm.
- Authors
Marmouset, Vincent; Joris, Magalie; Merlusca, Lavinia; Beaumont, Marie; Charbonnier, Amandine; Marolleau, Jean‐Pierre; Gruson, Bérengère; Marolleau, Jean-Pierre
- Abstract
We describe the use and value of a lenalidomide/bortezomib/dexamethasone regimen for the treatment of three patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN, a disease that lacks a consensus treatment). After five cycles of chemotherapy, we observed two complete responses and one clinical remission. Together with the encouraging literature data on the effects of lenalidomide and bortezomib on BPDCN cells, our results might prompt further investigations of this regimen's value in BPDCN.
- Subjects
DENDRITIC cells; TUMORS; BORTEZOMIB; THERAPEUTICS
- Publication
Hematological Oncology, 2019, Vol 37, Issue 4, p487
- ISSN
0278-0232
- Publication type
case study
- DOI
10.1002/hon.2671