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- Title
Viewing the bilayer hydrocarbon core using neutron diffraction.
- Authors
Xue Han; Hristova, Kalina; Han, Xue
- Abstract
Membrane proteins fold, assemble and function within their native fluid lipid environment. Structural studies of fluid lipid bilayers are thus critically important for understanding processes in membranes. Here, we propose a simple approach to visualize the hydrocarbon core using neutron diffraction and deuterated lipids that are commercially available. This method should have broad utility in structural studies of the bilayer response to protein insertion and folding in membranes.
- Subjects
MEMBRANE proteins; LIPIDS; HYDROCARBONS; NEUTRON diffraction; BILAYER lipid membranes; PHYSICAL &; theoretical chemistry; LECITHIN; RESEARCH funding
- Publication
Journal of Membrane Biology, 2009, Vol 227, Issue 3, p123
- ISSN
0022-2631
- Publication type
journal article
- DOI
10.1007/s00232-008-9151-3