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- Title
Toxic Epidermal Necrolysis with Prominent Facial Pustules: A Case with Reactivation of Human Herpesvirus 7.
- Authors
Honma, Masaru; Tobisawa, Shinichi; Iinuma, Shin; Shibuya, Takashi; Komatsu, Shigetsuna; Takahashi, Ichiro; Ishida-Yamamoto, Akemi; Iizuka, Hajime
- Abstract
A 37-year-old Japanese man presented with confluent erythemas and progressive erosive lesions on the almost entire body including the oral mucosa and genitalia. This was accompanied with prominent facial pustules. Although a lymphocyte stimulation test was positive only for acetaminophen, he took other agents including carbamazepine for his depression. He was diagnosed as having toxic epidermal necrolysis with prominent facial pustules and treated by methylprednisolone pulse therapy, which resulted in a good response. During the course, human herpesvirus 7 (HHV-7) DNA was detected in his peripheral blood. The HHV-7 reactivation might be related to facial pustulosis, which is occasionally observed in drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms. Copyright © 2010 S. Karger AG, Basel
- Publication
Dermatology (10188665), 2010, Vol 221, Issue 4, p306
- ISSN
1018-8665
- Publication type
Article
- DOI
10.1159/000319756