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- Title
Addictive personalities.
- Authors
Welberg, Leonie
- Abstract
The article investigates whether impulsivity and alternations in the dopamine system precede or follow drug abuse. A study showed that impulsive rats, which had never before been exposed to cocaine, self-administered more of the drug than non-impulsive rats. Moreover, the higher the rats’ pre-drug impulsivity levels, the fewer dopamine D2 and D3 receptors they had in the nucleus accumbens, a brain structure known to have a role in motivation and reward.
- Subjects
IMPULSIVE personality; PEOPLE with addiction; DOPAMINERGIC mechanisms; NUCLEUS accumbens; SUBSTANCE abuse; LABORATORY rats
- Publication
Nature Reviews Neuroscience, 2007, Vol 8, Issue 4, p246
- ISSN
1471-003X
- Publication type
Article
- DOI
10.1038/nrn2129