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- Title
Adiponectin Signaling Pathways in Liver Diseases.
- Authors
Gamberi, Tania; Magherini, Francesca; Modesti, Alessandra; Fiaschi, Tania
- Abstract
In the liver, adiponectin regulates both glucose and lipid metabolism and exerts an insulin-sensitizing effect. The binding of adiponectin with its specific receptors induces the activation of a proper signaling cascade that becomes altered in liver pathologies. This review describes the different signaling pathways in healthy and diseased hepatocytes, also highlighting the beneficial role of adiponectin in autophagy activation and hepatic regeneration.
- Subjects
ADIPONECTIN; LIVER disease treatment; LIVER cells; LIVER regeneration; HUMAN cellular signal transduction; DISEASES; THERAPEUTICS
- Publication
Biomedicines, 2018, Vol 6, Issue 2, p52
- ISSN
2227-9059
- Publication type
Article
- DOI
10.3390/biomedicines6020052