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- Title
Role of Salivary Biomarkers in Detection of Cardiovascular Diseases (CVD).
- Authors
Rehman, Saad Abdul; Khurshid, Zohaib; Niazi, Fayez Hussain; Naseem, Mustafa; Al Waddani, Hamed; Sahibzada, Haafsa Arshad; Khan, Rabia Sannam
- Abstract
Human whole mouth saliva (WMS) is secreted by salivary glands, namely parotid, submandibular/sublingual and other minor glands of the oral cavity. It is secreted in a systematic way, and contain informative proteins and peptides for the early detection of contagious diseases and organ-related diseases. The role of WMS as a liquid biopsy for the detection of cardiovascular diseases (CVD) through Myoglobin (MYO), Cardiac troponin I (cTnI), Creatine phosphokinase MB (CK-MB), Myeloperoxidase (MPO), brain natriuretic peptide (NT-proBNP), Exosomal miRNA, C-Reactive Protein (CRP), Matrix metalloproteinase-8 (MMP-8), MMP-9 and tissue inhibitor of MMP-8 (TIMP-1), leukotriene B4 has been well reported in last decade, that have been reviewed in the literature comprehensively below.
- Publication
Proteomes, 2017, Vol 5, Issue 3, p21
- ISSN
2227-7382
- Publication type
Article
- DOI
10.3390/proteomes5030021