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- Title
Application of Biosensors in Diagnosis of Human Parvoviruses.
- Authors
Hosseini, Fatemeh; Zandi, Milad; Behboudi, Emad; Salmanzadeh, Shokrollah; Rasooli, Azadeh; Abbasi, Aida; Abbasi, Samaneh
- Abstract
Human parvovirus B19 is a viral pathogen that causes acute and usually self-limiting disease. Because the B19 virus predicates erythroid progenitor cells, it can cause a transient aplastic crisis in immunocompromised individuals. This infection has been associated with nonimmunologic fetal hydrops during pregnancy; also, B19 can persist for months in immunocompromised individuals. In B19 infection, viremia with a high titer is observed for approximately one week. After that, a specific immune response is critical to control the infection. Although molecular and serologic tests commonly diagnose the B19 virus, laboratory diagnostic tests have limitations. For the detection of human parvovirus B19, an inexpensive, effective, and rapid biosensor may be considered as an alternative.
- Subjects
HYDROPS fetalis; PARVOVIRUSES; PARVOVIRUS B19; CLINICAL pathology; SERODIAGNOSIS; BIOSENSORS
- Publication
Journal of Liaquat University of Medical & Health Sciences, 2023, Vol 22, Issue 2, p89
- ISSN
1729-0341
- Publication type
Article
- DOI
10.22442/jlumhs.2023.01006