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The current state of molecular testing in the treatment of patients with solid tumors, 2019.
- Published in:
- 2019
- By:
- Publication type:
- journal article
BOOKS REVIEWS.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1992, v. 84, n. 12, p. 976
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- Publication type:
- Article
Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00150-8
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- Publication type:
- Article
Integrin/TGF-β1 Inhibitor GLPG-0187 Blocks SARS-CoV-2 Delta and Omicron Pseudovirus Infection of Airway Epithelial Cells In Vitro, Which Could Attenuate Disease Severity.
- Published in:
- Pharmaceuticals (14248247), 2022, v. 15, n. 5, p. 618, doi. 10.3390/ph15050618
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- Publication type:
- Article
Personalizing Colon Cancer Therapeutics: Targeting Old and New Mechanisms of Action.
- Published in:
- Pharmaceuticals (14248247), 2013, v. 6, n. 8, p. 988, doi. 10.3390/ph6080988
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- Publication type:
- Article
Pointing (zinc) fingers at BRCA1 targets.
- Published in:
- Nature Medicine, 2000, v. 6, n. 12, p. 1318, doi. 10.1038/82119
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- Publication type:
- Article
hADA3 is required for p53 activity.
- Published in:
- EMBO Journal, 2001, v. 20, n. 22, p. 6404, doi. 10.1093/emboj/20.22.6404
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- Publication type:
- Article
Advances in Liquid Biopsy Technology and Implications for Pancreatic Cancer.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 4238, doi. 10.3390/ijms24044238
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- Publication type:
- Article
Differential p53-Mediated Cellular Responses to DNA-Damaging Therapeutic Agents.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11828, doi. 10.3390/ijms222111828
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- Publication type:
- Article
ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R--mediated apoptosis.
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- Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2626, doi. 10.1172/JCI74056
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- Publication type:
- Article
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis.
- Published in:
- 2008
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- Publication type:
- journal article
Targeting mutant p53 shows promise for sunscreens and skin cancer.
- Published in:
- 2007
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- Publication type:
- journal article
Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.64958
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- Publication type:
- Article
Editorial: Expert opinions in genitourinary oncology.
- Published in:
- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2023.1360223
- By:
- Publication type:
- Article
Acute overexpression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells.
- Published in:
- International Journal of Cancer, 1998, v. 75, n. 6, p. 933, doi. 10.1002/(SICI)1097-0215(19980316)75:6<933::AID-IJC17>3.0.CO;2-3
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- Publication type:
- Article
In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug.
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- International Journal of Cancer, 1996, v. 67, n. 3, p. 386, doi. 10.1002/(SICI)1097-0215(19960729)67:3<386::AID-IJC13>3.0.CO;2-6
- By:
- Publication type:
- Article
ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases.
- Published in:
- Science Signaling, 2016, v. 9, n. 415, p. 1, doi. 10.1126/scisignal.aac4374
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- Publication type:
- Article
Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.
- Published in:
- Nature Genetics, 2003, v. 35, n. 3, p. 229, doi. 10.1038/ng1254
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- Publication type:
- Article
Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway.
- Published in:
- Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0346-9
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- Publication type:
- Article
Therapeutic Targeting of Autophagy in Pancreatic Ductal Adenocarcinoma.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.751568
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- Publication type:
- Article
Integrating Molecular Biomarker Inputs Into Development and Use of Clinical Cancer Therapeutics.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.747194
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- Publication type:
- Article
Targeting the Integrated Stress Response in Cancer Therapy.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.747837
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- Publication type:
- Article
Absence of Biomarker-Driven Treatment Options in Small Cell Lung Cancer, and Selected Preclinical Candidates for Next Generation Combination Therapies.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.747180
- By:
- Publication type:
- Article
First-In-Class Small Molecule ONC201 Induces DR5 and Cell Death in Tumor but Not Normal Cells to Provide a Wide Therapeutic Index as an Anti-Cancer Agent.
- Published in:
- PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0143082
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- Publication type:
- Article
Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075414
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- Publication type:
- Article
The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059380
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- Publication type:
- Article
Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor- Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0030207
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- Publication type:
- Article
p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.
- Published in:
- 2005
- By:
- Publication type:
- journal article
A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutatedp53.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.70429
- By:
- Publication type:
- Article
Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 4, p. 548, doi. 10.3390/biom12040548
- By:
- Publication type:
- Article
TRAIL and apoptosis induction by TNF-family death receptors.
- Published in:
- Oncogene, 2003, v. 22, n. 53, p. 8628, doi. 10.1038/sj.onc.1207232
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- Publication type:
- Article
Efficient growth inhibition of HPV 16 E6-expressing cells by an adenovirus-expressing p53 homologue p73ß.
- Published in:
- Oncogene, 2003, v. 22, n. 52, p. 8394, doi. 10.1038/sj.onc.1206908
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- Publication type:
- Article
The role of p53 in chemosensitivity and radiosensitivity.
- Published in:
- Oncogene, 2003, v. 22, n. 47, p. 7486, doi. 10.1038/sj.onc.1206949
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- Publication type:
- Article
P53 and radiation responses.
- Published in:
- Oncogene, 2003, v. 22, n. 37, p. 5774, doi. 10.1038/sj.onc.1206677
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- Publication type:
- Article
Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway.
- Published in:
- Oncogene, 2002, v. 21, n. 17, p. 2623, doi. 10.1038/sj.onc.1205345
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- Publication type:
- Article
Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.
- Published in:
- Oncogene, 2001, v. 20, n. 34, p. 4601, doi. 10.1038/sj.onc.1204484
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- Publication type:
- Article
Immunotherapy for Colorectal Cancer: Mechanisms and Predictive Biomarkers.
- Published in:
- Cancers, 2022, v. 14, n. 4, p. 1028, doi. 10.3390/cancers14041028
- By:
- Publication type:
- Article
Quassinoid analogs with enhanced efficacy for treatment of hematologic malignancies target the PI3Kγ isoform.
- Published in:
- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0996-z
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- Publication type:
- Article
Corrigendum: Clinical Utilization Pattern of Liquid Biopsies (LB) to Detect Actionable Driver Mutations, Guide Treatment Decisions and Monitor Disease Burden During Treatment of 33 Metastatic Colorectal Cancer (mCRC) Patients (pts) at a Fox Chase Cancer Center GI Oncology Subspecialty Clinic
- Published in:
- 2021
- By:
- Publication type:
- Correction Notice
Challenges in Diversity, Equity, and Inclusion in Research and Clinical Oncology.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.642112
- By:
- Publication type:
- Article
ERK and MDM2 prey on FOXO3a.
- Published in:
- Nature Cell Biology, 2008, v. 10, n. 2, p. 125, doi. 10.1038/ncb0208-125
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- Publication type:
- Article
Critical role for Daxx in regulating Mdm2.
- Published in:
- Nature Cell Biology, 2006, v. 8, n. 8, p. 855, doi. 10.1038/ncb1442
- By:
- Publication type:
- Article
BID regulation by p53 contributes to chemosensitivity.
- Published in:
- Nature Cell Biology, 2002, v. 4, n. 11, p. 842, doi. 10.1038/ncb866
- By:
- Publication type:
- Article
Akt takes centre stage in cell-cycle deregulation.
- Published in:
- Nature Cell Biology, 2001, v. 3, n. 3, p. E71, doi. 10.1038/35060148
- By:
- Publication type:
- Article
Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest.
- Published in:
- Oncogene, 1999, v. 18, n. 47, p. 6411, doi. 10.1038/sj.onc.1203025
- By:
- Publication type:
- Article
BRCA1 signals ARF-dependent stabilization and coactivation of p53.
- Published in:
- Oncogene, 1999, v. 18, n. 47, p. 6605, doi. 10.1038/sj.onc.1203284
- By:
- Publication type:
- Article
The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract.
- Published in:
- Oncogene, 1999, v. 18, n. 28, p. 4153, doi. 10.1038/sj.onc.1202763
- By:
- Publication type:
- Article
Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells.
- Published in:
- Oncogene, 1999, v. 18, n. 14, p. 2357, doi. 10.1038/sj.onc.1202543
- By:
- Publication type:
- Article
Potential role for Cathepsin D in p53-dependent tumor suppression and chemosensitivity.
- Published in:
- Oncogene, 1998, v. 16, n. 17, p. 2177, doi. 10.1038/sj.onc.1201755
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- Publication type:
- Article
BRCA1 physically associates with p53 and stimulates its transcriptional activity.
- Published in:
- Oncogene, 1998, v. 16, n. 13, p. 1713, doi. 10.1038/sj.onc.1201932
- By:
- Publication type:
- Article