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- Title
SMALL CELL LUNG CANCER: Paraneoplastic neurologic syndromes.
- Authors
Brade, Anthony
- Abstract
Paraneoplastic neurologic syndromes (PNS) are a rare manifestation of cancer, are thought to be the result of immune responses and have been associated with the presence of onconeural antibodies. "Classical" PNS are those with well-documented associations to onconeural antibodies. The majority of patients diagnosed with PNS initially present with a neurologic complaint, with subsequent evaluation leading to a diagnosis of lung cancer. A high level of suspicion is required for the appropriate diagnosis and management of the underlying malignancy. To date, a paucity of knowledge regarding PNS may lead to delayed diagnosis with a subsequent impact on prognosis. This review will provide a discussion of the prevalence, clinical presentation, diagnostic assessment and management considerations for patients with PNS in small cell lung cancer (SCLC).
- Subjects
SMALL cell lung cancer; PARANEOPLASTIC syndromes; CANCER diagnosis; DISEASE prevalence; IMMUNE response
- Publication
Oncology Exchange, 2012, Vol 11, Issue 1, pS.7
- ISSN
1705-2394
- Publication type
Article