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- Title
Effect of silver nanoparticles synthesized from Morinda citrifolia and irrigants against Streptococcus mutans biofilm.
- Authors
Pala, Vasishta; Vishnupriya, V.; Selvaraj, J.; Ponnulakshmi, R.; Gayathri, R.; Madhan, K.; Shyamaladevi, B.
- Abstract
Background: Morinda citrifolia is a fruit-bearing tree in the coffee family, Rubiaceae. Silver nanoparticles (AgNPs) are used as carriers for delivering various payloads to specific targets. AgNPs showed more inhibitory actions against human pathogens than crude plant extract; this shows the antimicrobial value against pathogenic diseases. Aim: The study was aimed at assessing the antimicrobial activity of M. citrifolia coated AgNPs against Streptococcus mutans species. Materials and Methods: S. mutans biofilm formation: S. mutans UA159 was cultured in brain heart infusion medium in a favorable condition to form a biofilm and they were cultured aerobically at 37°C for 2 days for colony-forming unit counting. Minimum inhibitory concentration of M. citrifolia extract was examined against S. mutans. Inhibition potential of the extract on preformed biofilm was analyzed. Results: The AgNPs coated with M. citrifolia extract showed the greatest inhibition effect at high concentration. The inhibitory activity increases with increase in concentration of the extract. Conclusion: The AgNPs had a comparatively good inhibitory power, even though ciprofloxacin had higher inhibition, M. citrifolia coated NPs can be used because they are naturally synthesized and does not have any side effects.
- Subjects
MORINDA citrifolia; SILVER nanoparticles; STREPTOCOCCUS mutans; DRUG side effects; HUMAN behavior; PLANT extracts
- Publication
Drug Invention Today, 2019, Vol 12, Issue 5, p920
- ISSN
0975-7619
- Publication type
Article