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Erratum to: The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019).
Published in:
2016
By:
- Gardenbroek, Tjibbe J.;
- Pinkney, Thomas D.;
- Sahami, Saloomeh;
- Morton, Dion G.;
- Buskens, Christianne J.;
- Ponsioen, Cyriel Y.;
- Tanis, Pieter J.;
- Löwenberg, Mark;
- van den Brink, Gijs R.;
- Broeders, Ivo A. M. J.;
- Pullens, Hendrikus J. M.;
- Seerden, Tom;
- Boom, Maarten J.;
- Mallant-Hent, Rosalie C.;
- Pierik, Robert E. G. J. M.;
- Vecht, Juda;
- Sosef, Meindert N.;
- van Nunen, Annick B.;
- van Wagensveld, Bart A.;
- Stokkers, Pieter C. F.
Publication type:
corrected article
The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019).
Published in:
BMC Surgery, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12893-015-0017-1
By:
- Gardenbroek, Tjibbe J.;
- Pinkney, Thomas D.;
- Sahami, Saloomeh;
- Morton, Dion G.;
- Buskens, Christianne J.;
- Ponsioen, Cyriel Y.;
- Tanis, Pieter J.;
- Löwenberg, Mark;
- den Brink, Gijs R. van;
- Broeders, Ivo A. M. J.;
- Pullens, Paul H. J. M.;
- Seerden, Tom;
- Boom, Maarten J.;
- Mallant-Hent, Rosalie C.;
- Pierik, Robert E. G. J. M.;
- Vecht, Juda;
- Sosef, Meindert N.;
- van Nunen, Annick B.;
- van Wagensveld, Bart A.;
- Stokkers, Pieter C. F.
Publication type:
Article
The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019).
Published in:
2015
By:
- Gardenbroek, Tjibbe J;
- Pinkney, Thomas D;
- Sahami, Saloomeh;
- Morton, Dion G;
- Buskens, Christianne J;
- Ponsioen, Cyriel Y;
- Tanis, Pieter J;
- Löwenberg, Mark;
- van den Brink, Gijs R;
- Broeders, Ivo Amj;
- Pullens, Paul Hjm;
- Seerden, Tom;
- Boom, Maarten J;
- Mallant-Hent, Rosalie C;
- Pierik, Robert Egjm;
- Vecht, Juda;
- Sosef, Meindert N;
- van Nunen, Annick B;
- van Wagensveld, Bart A;
- Stokkers, Pieter Cf
Publication type:
journal article
Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis.
Published in:
Stem Cells, 2011, v. 29, n. 10, p. 1549, doi. 10.1002/stem.698
By:
- Duijvestein, Marjolijn;
- Wildenberg, Manon E.;
- Welling, Mick M.;
- Hennink, Simone;
- Molendijk, Ilse;
- van Zuylen, Vanessa L.;
- Bosse, Tjalling;
- Vos, Anne Christine W.;
- de Jonge-Muller, Eveline S. M.;
- Roelofs, Helene;
- van der Weerd, Louise;
- Verspaget, Hein W.;
- Fibbe, Willem E.;
- te Velde, Anje A.;
- van den Brink, Gijs R.;
- Hommes, Daniel W.
Publication type:
Article
Linking pathways in colorectal cancer.
Published in:
Nature Genetics, 2004, v. 36, n. 10, p. 1038, doi. 10.1038/ng1004-1038
By:
- van den Brink, Gijs R.
Publication type:
Article
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation.
Published in:
Nature Genetics, 2004, v. 36, n. 3, p. 277, doi. 10.1038/ng1304
By:
- Schepman, Berber L.;
- Offerhaus, G. Johan;
- Keller, Josbert J.;
- Nielsen, Corinne;
- Gaffield, William;
- Roberts, Drucilla J.;
- Peppelenbosch, Maikel P.;
- Hardwick, James C. H.;
- van Deventer, Sander J. H.;
- van den Brink, Gijs R.;
- Bleuming, Sylvia A.
Publication type:
Article
Intestinal Tumorigenesis Is Not Affected by Progesterone Signaling in Rodent Models.
Published in:
PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022620
By:
- Heijmans, Jarom;
- Muncan, Vanesa;
- Jacobs, Rutger J.;
- de Jonge-Muller, Eveline S. M.;
- Graven, Laura;
- Biemond, Izak;
- Ederveen, Antwan G.;
- Groothuis, Patrick G.;
- Mosselman, Sietse;
- Hardwick, James C.;
- Hommes, Daniel W.;
- van den Brink, Gijs R.
Publication type:
Article
MEX3A regulates Lgr5<sup>+</sup> stem cell maintenance in the developing intestinal epithelium.
Published in:
EMBO Reports, 2020, v. 21, n. 4, p. 1, doi. 10.15252/embr.201948938
By:
- Pereira, Bruno;
- Amaral, Ana L;
- Dias, Alexandre;
- Mendes, Nuno;
- Muncan, Vanesa;
- Silva, Ana R;
- Thibert, Chantal;
- Radu, Anca G;
- David, Leonor;
- Máximo, Valdemar;
- van den Brink, Gijs R;
- Billaud, Marc;
- Almeida, Raquel
Publication type:
Article
Mouse fetal intestinal organoids: new model to study epithelial maturation from suckling to weaning.
Published in:
EMBO Reports, 2019, v. 20, n. 2, p. N.PAG, doi. 10.15252/embr.201846221
By:
- Navis, Marit;
- Martins Garcia, Tânia;
- Renes, Ingrid B;
- Vermeulen, Jacqueline LM;
- Meisner, Sander;
- Wildenberg, Manon E;
- van den Brink, Gijs R;
- van Elburg, Ruurd M;
- Muncan, Vanesa
Publication type:
Article
Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.
Published in:
Life Science Alliance, 2023, v. 6, n. 11, p. 1, doi. 10.26508/lsa.202301912
By:
- Spaan, Claudia N.;
- de Boer, Ruben J.;
- Smit, Wouter L.;
- van der Meer, Jonathan H. M.;
- van Roest, Manon;
- Vermeulen, Jacqueline L. M.;
- Koelink, Pim J.;
- Becker, Marte A. J.;
- Go, Simei;
- Silva, Joana;
- Faller, William J.;
- van den Brink, Gijs R.;
- Muncan, Vanesa;
- Heijmans, Jarom
Publication type:
Article
NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps.
Published in:
Oncogene, 2001, v. 20, n. 7, p. 819, doi. 10.1038/sj.onc.1204162
By:
- Hardwick, James CH;
- van den Brink, Gijs R;
- Offerhaus, G J;
- van Deventer, Sander JH;
- Peppelenbosch, Maikel P
Publication type:
Article
The Bone Morphogenetic Protein Pathway Is Active in Human Colon Adenomas and Inactivated in Colorectal Cancer.
Published in:
Cancer (0008543X), 2008, v. 112, n. 2, p. 300, doi. 10.1002/cncr.23160
By:
- Kodach, Liudmila L.;
- Bleuming, Sylvia A.;
- Musler, Alex R.;
- Peppelenbosch, Maikel P.;
- Hommes, Daniel W.;
- Van Den Brink, Gijs R.;
- Van Noesel, Carel J. M.;
- Offerhaus, G. Johan A.;
- Hardwick, James C. H.
Publication type:
Article
HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.
Published in:
FASEB Journal, 2015, v. 29, n. 5, p. 2070, doi. 10.1096/fj.14-257931
By:
- Zimberlin, Cheryl D.;
- Lancini, Cesare;
- Sno, Rachel;
- Rosekrans, Sanne L.;
- McLean, Chelsea M.;
- Vlaming, Hanneke;
- den Brink, Gijs R. van;
- Bots, Michael;
- Medema, Jan Paul;
- Dannenberg, Jan-Hermen
Publication type:
Article
The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer.
Published in:
Carcinogenesis, 2010, v. 31, n. 9, p. 1567, doi. 10.1093/carcin/bgq147
By:
- Kodach, Liudmila L.;
- Jacobs, Rutger J.;
- Heijmans, Jarom;
- van Noesel, Carel J. M.;
- Langers, Alexandra M. J.;
- Verspaget, Hein W.;
- Hommes, Daniel W.;
- Offerhaus, G. Johan A.;
- van den Brink, Gijs R.;
- Hardwick, James C. H.
Publication type:
Article
Erratum: Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Published in:
Nature Communications, 2016, v. 7, n. 9, p. 12936, doi. 10.1038/ncomms12936
By:
- Gerling, Marco;
- Büller, Nikè V.J.A.;
- Kirn, Leonard M;
- Joost, Simon;
- Frings, Oliver;
- Englert, Benjamin;
- Bergström, Åsa;
- Kuiper, Raoul V.;
- Blaas, Leander;
- Wielenga, Mattheus C. B.;
- Almer, Sven;
- Kühl, Anja A.;
- Fredlund, Erik;
- van den Brink, Gijs R.;
- Toftgård, Rune
Publication type:
Article
Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Published in:
Nature Communications, 2016, v. 7, n. 8, p. 12321, doi. 10.1038/ncomms12321
By:
- Gerling, Marco;
- Büller, Nikè V. J. A.;
- Kirn, Leonard M.;
- Joost, Simon;
- Frings, Oliver;
- Englert, Benjamin;
- Bergström, Åsa;
- Kuiper, Raoul V.;
- Blaas, Leander;
- Wielenga, Mattheus C. B.;
- Almer, Sven;
- Kühl, Anja A.;
- Fredlund, Erik;
- van den Brink, Gijs R.;
- Toftgård, Rune
Publication type:
Article
Study of calcium signaling in non-excitable cells.
Published in:
Microscopy Research & Technique, 1999, v. 46, n. 6, p. 418, doi. 10.1002/(SICI)1097-0029(19990915)46:6<418::AID-JEMT9>3.0.CO;2-0
By:
- Van Den Brink, Gijs R.;
- Bloemers, S. Margreet;
- Van Den Blink, Bernt;
- Tertoolen, Leon G.J.;
- Van Deventer, Sander J.H.;
- Peppelenbosch, Maikel P.
Publication type:
Article
Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89326-w
By:
- Meijer, Bartolomeus J.;
- Smit, Wouter L.;
- Koelink, Pim J.;
- Westendorp, Barbara F.;
- de Boer, Ruben J.;
- van der Meer, Jonathan H. M.;
- Vermeulen, Jacqueline L. M.;
- Paton, James C.;
- Paton, Adrienne W.;
- Qin, Jun;
- Dekker, Evelien;
- Muncan, Vanesa;
- van den Brink, Gijs R.;
- Heijmans, Jarom
Publication type:
Article
Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis.
Published in:
Cell Death & Disease, 2021, v. 12, n. 10, p. 1, doi. 10.1038/s41419-021-04173-x
By:
- van der Meer, Jonathan H. M.;
- de Boer, Ruben J.;
- Meijer, Bartolomeus J.;
- Smit, Wouter L.;
- Vermeulen, Jacqueline L. M.;
- Meisner, Sander;
- van Roest, Manon;
- Koelink, Pim J.;
- Dekker, Evelien;
- Hakvoort, Theodorus B. M.;
- Koster, Jan;
- Hawinkels, Lukas J. A. C.;
- Heijmans, Jarom;
- Struijs, Eduard A.;
- Boermeester, Marja A.;
- van den Brink, Gijs R.;
- Muncan, Vanesa
Publication type:
Article
Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling.
Published in:
Cell Death & Disease, 2019, v. 10, n. 7, p. N.PAG, doi. 10.1038/s41419-019-1729-4
By:
- Spaan, Claudia N.;
- Smit, Wouter L.;
- van Lidth de Jeude, Jooske F.;
- Meijer, Bartolomeus J.;
- Muncan, Vanesa;
- van den Brink, Gijs R.;
- Heijmans, Jarom
Publication type:
Article
Regulatory regions in the rat lactase-phlorizin hydrolase gene that control cell-specific expression.
Published in:
2004
By:
- Verhave, Menno;
- Krasinski, Stephen D.;
- Christian, Sara I.;
- Van Schaik, Sandrijn;
- van Den Brink, Gijs R.;
- Doting, Edwina M. H.;
- Maas, Saskia M.;
- Wolthers, Katja C.;
- Grand, Richard J.;
- Montgomery, Robert K.
Publication type:
journal article
Evaluation of optimal biopsy location for assessment of histological activity, transcriptomic and immunohistochemical analyses in patients with active Crohn's disease.
Published in:
Alimentary Pharmacology & Therapeutics, 2019, v. 49, n. 11, p. 1401, doi. 10.1111/apt.15250
By:
- Novak, Gregor;
- Stevens, Toer;
- Van Viegen, Tanja;
- Bossuyt, Peter;
- Štabuc, Borut;
- Jeyarajah, Jenny;
- Zou, Guangyong;
- Gaemers, Ingrid C.;
- McKee, Trevor D.;
- Fu, Fred;
- Shackelton, Lisa M.;
- Khanna, Reena;
- van den Brink, Gijs R.;
- Sandborn, William J.;
- Feagan, Brian G.;
- Pai, Rish K.;
- Jairath, Vipul;
- Vande Casteele, Niels;
- D'Haens, Geert
Publication type:
Article
Persistent Mesorectal Inflammatory Activity is Associated With Complications After Proctectomy in Crohn's Disease.
Published in:
Journal of Crohn's & Colitis, 2019, v. 13, n. 3, p. 285, doi. 10.1093/ecco-jcc/jjy131
By:
- Groof, E Joline de;
- Meer, Jonathan H M van der;
- Tanis, Pieter J;
- Bruyn, Jessica R de;
- Ruler, Oddeke van;
- D'Haens, Geert R A M;
- Brink, Gijs R van den;
- Bemelman, Willem A;
- Wildenberg, Manon E;
- Buskens, Christianne J
Publication type:
Article
Development of Reliable, Valid and Responsive Scoring Systems for Endoscopy and Histology in Animal Models for Inflammatory Bowel Disease.
Published in:
Journal of Crohn's & Colitis, 2018, v. 12, n. 7, p. 794, doi. 10.1093/ecco-jcc/jjy035
By:
- Koelink, Pim J.;
- Wildenberg, Manon E.;
- Stitt, Larry W.;
- Feagan, Brian G.;
- Koldijk, Martin;
- van 't Wout, Angélique B.;
- Atreya, Raja;
- Vieth, Michael;
- Brandse, Johannan F.;
- Duijst, Suzanne;
- Velde, Anje A. te;
- D'Haens, Geert R. A. M.;
- Levesque, Barrett G.;
- den Brink, Gijs R. van
Publication type:
Article
Fibrostenotic Phenotype of Myofibroblasts in Crohn's Disease is Dependent on Tissue Stiffness and Reversed by LOX Inhibition.
Published in:
Journal of Crohn's & Colitis, 2018, v. 12, n. 7, p. 849, doi. 10.1093/ecco-jcc/jjy036
By:
- de Bruyn, Jessica R.;
- van den Brink, Gijs R.;
- Steenkamer, Jessica;
- Buskens, Christianne J.;
- Bemelman, Willem A.;
- Meisner, Sander;
- Muncan, Vanesa;
- Velde, Anje A. te;
- D'Haens, Geert R.;
- Wildenberg, Manon E.
Publication type:
Article
Benzimidazoles Promote Anti-TNF Mediated Induction of Regulatory Macrophages and Enhance Therapeutic Efficacy in a Murine Model.
Published in:
Journal of Crohn's & Colitis, 2017, v. 11, n. 12, p. 1480, doi. 10.1093/ecco-jcc/jjx104
By:
- Wildenberg, Manon E.;
- Levin, Alon D.;
- Ceroni, Alessandro;
- Zhen Guo;
- Koelink, Pim J.;
- Hakvoort, Theodorus B. M.;
- Westera, Liset;
- Bloemendaal, Felicia M.;
- Brandse, Johannan F.;
- Simmons, Alison;
- D'Haens, Geert R.;
- Ebner, Daniel;
- van den Brink, Gijs R.
Publication type:
Article
Mechanism of Action of Anti-TNF Therapy in Inflammatory Bowel Disease.
Published in:
Journal of Crohn's & Colitis, 2016, v. 10, n. 8, p. 989, doi. 10.1093/ecco-jcc/jjw053
By:
- Levin, Alon D.;
- Wildenberg, Manon E.;
- van den Brink, Gijs R.
Publication type:
Article
Results of the Fifth Scientific Workshop of the ECCO [II]: Clinical Aspects of Perianal Fistulising Crohn's Disease--the Unmet Needs.
Published in:
Journal of Crohn's & Colitis, 2016, v. 10, n. 7, p. 758, doi. 10.1093/ecco-jcc/jjw039
By:
- Gecse, Krisztina B.;
- Sebastian, Shaji;
- de Hertogh, Gert;
- Yassin, Nuha A.;
- Kotze, Paulo G.;
- Reinisch, Walter;
- Spinelli, Antonino;
- Koutroubakis, Ioannis E.;
- Katsanos, Konstantinos H.;
- Hart, Ailsa;
- van den Brink, Gijs R.;
- Rogler, Gerhard;
- Bemelman, Willem A.
Publication type:
Article
Similar Short- and Long-term Colectomy Rates with Ciclosporin and Infliximab Treatment in Hospitalised Ulcerative Colitis Patients.
Published in:
Journal of Crohn's & Colitis, 2016, v. 10, n. 7, p. 821, doi. 10.1093/ecco-jcc/jjw031
By:
- Duijvis, Nicolette W.;
- ten Hove, Anne S.;
- Ponsioen, Cyriel I. J.;
- van den Brink, Gijs R.;
- Buskens, Christianne J.;
- Bemelman, Willem A.;
- te Velde, Anje A.;
- D'Haens, Geert R. A. M.;
- Löwenberg, Mark
Publication type:
Article
Autophagy Contributes to the Induction of Anti-TNF Induced Macrophages.
Published in:
Journal of Crohn's & Colitis, 2016, v. 10, n. 3, p. 323, doi. 10.1093/ecco-jcc/jjv174
By:
- Levin, Alon D.;
- Koelink, Pim J.;
- Bloemendaa, Felicia M.;
- Vos, Anne Christine W.;
- D'Haens, Geert R.;
- van den Brink, Gijs R.;
- Wildenberga, Manon E.
Publication type:
Article
Fc Receptor-mediated Effector Function Contributes to the Therapeutic Response of Anti-TNF Monoclonal Antibodies in a Mouse Model of Inflammatory Bowel Disease.
Published in:
Journal of Crohn's & Colitis, 2016, v. 10, n. 1, p. 69, doi. 10.1093/ecco-jcc/jjv179
By:
- McRae, Bradford L.;
- Levin, Alon D.;
- Wildenberg, Manon E.;
- Koelink, Pim J.;
- Bousquet, Peter;
- Mikaelian, Igor;
- Sterman, Annette Schwartz;
- Bryant, Shaughn;
- D'Haens, Geert;
- Kamath, Rajesh;
- Salfeld, Jochen;
- den Brink, Gijs R. van
Publication type:
Article
Serum Concentration of Anti-TNF Antibodies, Adverse Effects and Quality of Life in Patients with Inflammatory Bowel Disease in Remission on Maintenance Treatment.
Published in:
Journal of Crohn's & Colitis, 2015, v. 9, n. 11, p. 973, doi. 10.1093/ecco-jcc/jjv116
By:
- Brandse, Johannan F.;
- Vos, Laura M. C.;
- Jansen, Jeroen;
- Schakel, Toos;
- Ponsioen, Cyriel I. J.;
- van den Brink, Gijs R.;
- D'Haens, Geert R.;
- Löwenberg, Mark
Publication type:
Article
Development of Fibrosis in Acute and Longstanding Ulcerative Colitis.
Published in:
Journal of Crohn's & Colitis, 2015, v. 9, n. 11, p. 966, doi. 10.1093/ecco-jcc/jjv133
By:
- de Bruyn, Jessica R.;
- Meijer, Sybren L.;
- Wildenberg, Manon E.;
- Bemelman, Willem A.;
- van den Brink, Gijs R.;
- D'Haens, Geert R.
Publication type:
Article
Vitamin D deficiency in Crohn's disease and healthy controls: A prospective case–control study in the Netherlands.
Published in:
Journal of Crohn's & Colitis, 2014, v. 8, n. 10, p. 1267, doi. 10.1016/j.crohns.2014.03.004
By:
- de Bruyn, Jessica R.;
- van Heeckeren, Rosanne;
- Ponsioen, Cyriel Y.;
- van den Brink, Gijs R.;
- Löwenberg, Mark;
- Bredenoord, Albert J.;
- Frijstein, Gerard;
- D’Haens, Geert R.
Publication type:
Article
Management of Lack and Loss of Response to Anti-Tumor Necrosis Factor Therapy.
Published in:
Inflammatory Bowel Disease Monitor, 2009, v. 10, n. 2, p. 43
By:
- Vos, Anne Christine W.;
- Fidder, Herma H.;
- van den Brink, Gijs R.;
- Hommes, Daniel W.
Publication type:
Article
Bone morphogenetic protein signalling in colorectal cancer.
Published in:
Nature Reviews Cancer, 2008, v. 8, n. 10, p. 806, doi. 10.1038/nrc2467
By:
- Hardwick, James C.;
- Kodach, Liudmila L.;
- Offerhaus, G. Johan;
- Van den Brink, Gijs R.
Publication type:
Article
Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190999
By:
- de Bruyn, Jessica R.;
- Becker, Marte A.;
- Steenkamer, Jessica;
- Wildenberg, Manon E.;
- Meijer, Sybren L.;
- Buskens, Christianne J.;
- Bemelman, Willem A.;
- Löwenberg, Mark;
- Ponsioen, Cyriel Y.;
- van den Brink, Gijs R.;
- D’Haens, Geert R.
Publication type:
Article

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