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- Title
Intraoral hemorrhagic bullae as the first sign of immunoglobulin light chain amyloidosis.
- Authors
Dominguez-Lopez, Raquel María; Naharro-Rodriguez, Jorge
- Abstract
This article discusses a case study of a 76-year-old woman who presented with painless intraoral bullae, which were the first sign of immunoglobulin light chain amyloidosis. The patient also experienced unintentional weight loss and weakness. The article explains that mucocutaneous manifestations, such as purpuric lesions and hemorrhagic bullae, can occur in cases of immunoglobulin light chain amyloidosis. Treatment options depend on eligibility for autologous stem cell transplantation, and if diagnosed at an advanced stage, the prognosis can be poor.
- Subjects
IMMUNOGLOBULIN light chains; AMYLOIDOSIS; CARDIAC amyloidosis; MONOCLONAL gammopathies
- Publication
Canadian Medical Association Journal (CMAJ), 2024, Vol 196, Issue 20, pE705
- Publication type
Article
- DOI
10.1503/cmaj.240119