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- Title
Influenţa administrării de flavonoizi asupra capacităţii de efort la şobolani.
- Authors
Kiss, Mihai; Dragoş, Ovidiu; Mureşan, Adriana; Orşsan, Remus
- Abstract
Background. The antioxidant role of flavonoids, demonstrated particularly in vitro, justifies the studies on their potential protective effects under physical exercise conditions associated with oxidative and nitrosative stress. Aims. The influence of the administration of flavonoids on the aerobic exercise capacity was studied in rats performing physical exercises of various intensities. Material and methods. The research was performed on 5 groups of white male Wistar rats (n = 10 animals/group) trained on the treadmill for 21 days: group I - control group; group II - supplemented with flavonoids; groups III, IV and V - supplemented with flavonoids, with 5%, 10% and 15% loading, respectively. The time moments included in the study were days 1, 3, 6, 9, 12, 15, 18 and 21. Results. The running time was significantly longer in group II compared to other groups on all days, except for T3, when it was not different from group I. The running time was significantly longer in group I compared to groups III, IV and V at T1, T3, T6 and T9, it was not different at T12, T15 and T18, and it was different at T21. The running time was significantly different between T1-T21, T3-T6, T6-T9, T9-T12, T15-T18, T18-T21 in all groups. The running time was significantly different between T1-T3 and T12-T15 in all groups, except for group II. Conclusions. 1) Flavonoids have significant ergotropic effects, in animals undergoing physical exercise tests without loading for 21 days. 2) The administration of flavonoids and concomitant physical exercise for 21 days with 5%, 10% and 15% loading, respectively, causes a diminution in the ergotropic effects of flavonoids.
- Subjects
FLAVONOIDS; ANTIOXIDANTS; AEROBIC exercises; AEROBIC capacity; LABORATORY rats; CONTROL groups
- Publication
Palestrica of the Third Millennium Civilization & Sport, 2011, Vol 12, Issue 1, p21
- ISSN
1582-1943
- Publication type
Article