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- Title
A Randomized Controlled Trial of Behavioral Weight Loss Treatment Versus Combined Weight Loss/Depression Treatment Among Women with Comorbid Obesity and Depression.
- Authors
Linde, Jennifer A.; Simon, Gregory E.; Ludman, Evette J.; Ichikawa, Laura E.; Operskalski, Belinda H.; Arterburn, David; Rohde, Paul; Finch, Emily A.; Jeffery, Robert W.
- Abstract
Background: Obesity is associated with clinical depression among women. However, depressed women are often excluded from weight loss trials. Purpose: This study examined treatment outcomes among women with comorbid obesity and depression. Methods: Two hundred three (203) women were randomized to behavioral weight loss ( n = 102) or behavioral weight loss combined with cognitive-behavioral depression management ( n = 101). Results: Average participant age was 52 years; mean baseline body mass index was 39 kg/m. Mean Patient Health Questionnaire and Hopkins Symptom Checklist (SCL-20) scores indicated moderate to severe baseline depression. Weight loss and SCL-20 changes did not differ between groups at 6 or 12 months in intent-to-treat analyses ( p = 0.26 and 0.55 for weight, p = 0.70 and 0.25 for depressive symptoms). Conclusions: Depressed obese women lost weight and demonstrated improved mood in both treatment programs. Future weight loss trials are encouraged to enroll depressed women.
- Subjects
WEIGHT loss; OVERWEIGHT women; DEPRESSION in women; MOOD (Psychology); RANDOMIZED controlled trials; THERAPEUTICS
- Publication
Annals of Behavioral Medicine, 2011, Vol 41, Issue 1, p119
- ISSN
0883-6612
- Publication type
Article
- DOI
10.1007/s12160-010-9232-2