We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Comparative immunology of human and animal models of hookworm infection.
- Authors
Fujiwara, R. T.; Geiger, S. M.; Bethony, J.; Mendez, S.
- Abstract
Hookworm infection is a major cause of disease burden for animals and humans. Over the past years, the use of animal models in hookworm infections has been driven by the search of new anthelminthic therapies and, especially, vaccine development. These studies also contributed to the advance of knowledge on immunity to hookworms, offering new insights to understand the nature of this parasitic infection. In this article, we will summarize the essential features of the immune response in the two major animal models of hookworm infections (dog and hamster) and then consider its implication for the human immune response.
- Subjects
HOOKWORM disease; ANIMAL models of immunology; HUMAN beings; PARASITIC diseases; HOOKWORMS; VACCINES
- Publication
Parasite Immunology, 2006, Vol 28, Issue 7, p285
- ISSN
0141-9838
- Publication type
Article
- DOI
10.1111/j.1365-3024.2006.00821.x