Functional study on Boswellia phytosome as complementary intervention in asthmatic patients.

FERRARA, T.; DE VINCENTIIS, G.; DI PIERRO, F.

OBJECTIVE: The combination of inhaled corticosteroids (ICS) and long-acting beta-agonists (LABAs) is recommended for the treatment of patients with mild-to-severe persistent asthma. However, given the lack of definite and safe therapies, complementary or alternative medicines are frequently used by asthmatic patients in combination with standard treatments. PATIENTS AND METHODS: A group of asthmatic subjects have been enrolled in this multi-center study; after having verified the compliance to their current medical therapy (ICS LABAs), the subjects have been randomized to receive Casperome® 500 mg/day or no additional treatment for a period of 4 weeks. They were also asked to keep track of the number of inhalations required per day and any adverse events through a daily form. RESULTS: A total of 32 subjects were enrolled in the study. Subjects receiving Casperome® 500 mg/day in addition to the standard ICS LABAs treatment showed a decrease in the number of inhalations needed compared to patients who did not receive Casperome® therapy. The treatment was well tolerated and only mild-moderate adverse events were registered. CONCLUSIONS: The use of Casperome® 500 mg/day is beneficial for asthmatic patients as it helps reduce the need for inhalation therapy with ICS LABA.

BOSWELLIA; ASTHMATICS; ADRENOCORTICAL hormones; STEROID hormones; HORMONES

European Review for Medical & Pharmacological Sciences, 2015, Vol 19, Issue 19, p3757

1128-3602

Academic Journal