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- Title
Characterization of the murine orthologue of a novel human subtelomeric multigene family.
- Authors
Gianfrancesco, F.; Falco, G.; Esposito, T.; Rocchi, M.; D'Urso, M.
- Abstract
The genomes of most organisms contain multiple copies of genes that are closely related in structure and function. Such gene families can arise from tandem duplications, as in the case of the HOX clusters, or from ancient polyploidization events which occurred in primitive chordates. The reason why multiple copies of an intact gene in a particular genome are preserved is unclear although an increase of protein level may provide a selective advantage to the organism, maintaining extra copies in subsequent generations.
- Subjects
GENOMES; MARMOSA; POLYPLOIDY; NUCLEOTIDES; SEX chromosomes; GENE mapping
- Publication
Cytogenetics & Cell Genetics, 2001, Vol 94, Issue 1/2, p98
- ISSN
0301-0171
- Publication type
Article
- DOI
10.1159/000048796