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- Title
Guillain-Barre sendromu nedeniyle hastanede yatan bir hastada gelişen Burkholderia cepacia sepsisi.
- Authors
Baylan, Orhan; Selek, Mehmet Burak; Alay, Semih; Öncül, Oral; Özyurt, Mustafa; Haznedaroğlu, Tunçer
- Abstract
Burkholderia cepacia, is an opportunistic Gram-negative bacillus that causes necrotizing pneumonia, sepsis/bacteremia and epidemics especially in cystic fibrosis or immunosupressed patients hospitalized in intensive care units. In this report, a case of B. cepacia sepsis in an immunocompetent patient with a diagnosis of Guillain-Barre syndrome hospitalized in the neurological intensive care unit, is being presented. B. cepacia was isolated from three serial blood cultures taken at different times within 15 days. The antibiotic susceptibility testing of the isolates was performed by Kirby-Bauer disc diffusion method according to the "Clinical and Laboratory Standards Institute (CLSI)" criteria. The isolates were found to be susceptible to trimethoprim/sulfamethoxazole, ceftazidime and meropenem, and intermediately susceptible to minocycline. Doripenem was added to patient's ongoing combination treatment with colistin and levofloxacin. On the third day of the treatment, the patient started having fever and therefore the antibiotic therapy was prolonged for additional 14 days. At the end of the therapy, the patient was cured without any complication. In the mean time, the agent could not be isolated from any other environmental samples taken from the neurological intensive care unit. It should be kept in mind that B. cepacia sepsis can be seen in intensive care unit patients with prolonged hospitalization, indwelling catheters and medical devices, even if they are not immunosupressed.
- Subjects
GUILLAIN-Barre syndrome; NOSOCOMIAL infections; SEPSIS; BURKHOLDERIA cepacia; GRAM-negative bacteria; CYSTIC fibrosis
- Publication
Turkish Bulletin of Hygiene & Experimental Biology / Türk Hijyen ve Deneysel Biyoloji, 2011, Vol 68, Issue 4, p197
- ISSN
0377-9777
- Publication type
Article
- DOI
10.5505/TurkHijyen.2011.67799