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- Title
Rola czynników troficznych i procesów zapalnych w neuroprotekcji indukowanej wysiłkiem w chorobie Parkinsona.
- Authors
Pałasz, Ewelina; Bąk, Agnieszka; Gąsiorowska, Anna; Niewiadomska, Grażyna
- Abstract
Glial cells and neurotrophins play an important role in maintaining homeostasis of the CNS. Disturbances of their function can lead to a number of nervous system diseases, including Parkinson's disease (PD). Current clinical studies provide evidence that moderate physical activity adapted to the health status of PD patients can support pharmacological treatment, slow down the onset of motor impairments, and extend the patients period of independence. Physical activity, by stimulating the production and release of endogenous trophic factors, prevents the neurodegeneration of dopaminergic neurons via inhibition of inflammatory processes and the reduction of oxidative stress. The aim of this study is to present the current state of knowledge for the anti-inflammatory and neuroprotective properties of physical activity as a supportive therapy in Parkinson's disease.
- Publication
Advances in Hygiene & Experimental Medicine / Postepy Higieny i Medycyny Doswiadczalnej, 2017, Vol 71, p713
- ISSN
0032-5449
- Publication type
Article