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- Title
Effectiveness of Gail Model in Assessing the Risk of Developing Breast Cancer in Baghdad, Iraq.
- Authors
Al-jobawi, Zainab J.; Ali, Besmah M.; Juda, Abdulrahman I.; Alhusseini, Safra H.; Mohammed, Sabah J.
- Abstract
Background: The Gail Model is a statistical breast cancer risk assessment algorithm that was developed in 1989 by Dr. Mitchell Gail and colleagues with the Biostatistics Branch of the National Cancer Institute’s Division of Cancer Epidemiology and Genetics. The Gail Model looked at a woman’s personal medical history, familial history, and reproductive history. The Gail model has been widely used and validated with conflicting results. Method: A Gail model were assessed for 200 convenient patients, 100 patients with history of breast cancer diagnosed during the last year (case) and other 100 patients with benign breast disease (control) and who attended the oncology hospital in medical city and Imamin Al-kadhimin medical city during 2019. The relative risk was measure for each patients and calculated 5 year risk >1.7% was regard as high risk, chisquare and student T test was used to find association between two groups. Results: Calculated 5 year risk >1.7% found in 21% of case and in 11% of control and no association was found between two groups in the relative risk of breast cancer (χ2 = 3.7, df = 1, p = 0.054). Conclusions: The Gail model is not useful in identifying risk of breast cancer in women and should not be used for that purpose.
- Subjects
BAGHDAD (Iraq); BREAST cancer; CANCER genetics; EPIDEMIOLOGY of cancer; REPRODUCTIVE history; RISK assessment
- Publication
Indian Journal of Public Health Research & Development, 2020, Vol 11, Issue 3, p2557
- ISSN
0976-0245
- Publication type
Article