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- Title
Clinico-Epidemiological Study of Oral Potentially Malignant and Malignant Lesions in a Tertiary Care Centre of Odisha- A Five Year Longitudinal Study.
- Authors
Debta, Fakir Mohan; Debta, Priyanka; Mishra, Ekagrata; Swain, Santosh Kumar; Sahu, Mahesh Chandra; Samal, Smrutipragnya; Dani, Anurag
- Abstract
Introduction: The nomenclature of potentially malignant disorders (PMDs) of the oral mucosa, with the risk of conversion to oral squamous cell carcinoma (OSCC) have been very diverse. Despite the ability to identify PMD, clinicians have been unable to predict the behavior of lesions or quantify the risk of malignant transformation. This study aims to qualitatively and quantitatively over a five year period using clinical spectrum of presentation and frequency distribution, prevalence, malignant transformation rates of PMD’s. Materials and Method: This study follows a longitudinal prospective study design which was conducted in the Department of Oral Medicine, Oral Diagnosis and Radiology, at S.C.B. Dental College and Hospital, Cuttack over 5 years, from January 2013 to December 2017. The study intended to primarily address and document the clinical diversity, 5year frequency distribution, prevalence, malignant transformation rates of OPMD’s. Results: The frequency of OPMD’s was 55% with 36.88 % males. The most and least frequently encountered OPMD included Pouch keratosis (30.96% of OPMD’s) and Discoid Lupus Erythematosus (0.002% of OPMD’s). The mean age of malignant transformation was 41 years with a male predilection (68 %) and was largely habit associated (72%). Over the 5 year period the highest rate of malignant transformation was observed for actinic chelitis (20.66%) and least for oral lichen planus (0.35%). Discussion and Conclusion: During the 5 year study period, 55.01% were OPMD’s and 6.34% were head and neck cancers. The significantly higher rate of transformation noted in our population can be attributed to late presentation for treatment, rampant production and continued use of smokeless forms of tobacco. To the best of our knowledge, this study is one of the few to recruit a large population presenting with varied lesions.
- Publication
Indian Journal of Public Health Research & Development, 2018, Vol 9, Issue 11, p2127
- ISSN
0976-0245
- Publication type
Article
- DOI
10.5958/0976-5506.2018.01765.5