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- Title
Application and Characterization of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as Drug Delivery Systems.
- Authors
Kelidari, Hamid Reza; Akbari, Jafar; Saeedi, Majid
- Abstract
Nowadays solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) have been investigated as carrier systems for many applications. SLNs consist of pure solid lipids, while NLCs are made of a solid matrix that entraps liquid lipid nano-compartments. These systems revealed several advantages compared to other colloidal carrier systems. They provide a controlled drug release and an increase in chemical stability of the incorporated drugs. Moreover, they are safe carriers which can be produced easily in a large scale. This paper reviews the commonly used materials, production techniques, characterization, and physical stability of these systems.
- Subjects
LIPIDS; DRUG delivery systems; NANOMEDICINE; CONTROLLED release drugs; COLLOIDS in medicine; CHEMICAL stability
- Publication
Journal of Mazandaran University of Medical Sciences (JMUMS), 2013, Vol 23, Issue 98, p386
- ISSN
1735-9260
- Publication type
Article