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- Title
Anecdotal Response to Amphotericin in a Patient with Probable Susac Syndrome: Implications in the Pathogenesis.
- Authors
GIL-GOUVEIAH, Raquel; MARTO, Natália; VILELA, Pedro; CATARINO, Ana
- Abstract
Susac syndrome is a rare, probably immune-mediated endotheliopathy presenting with encephalopathy, sensorineural hearing loss and retinal arterial occlusions. A 33-year-old female with Susac syndrome was worsening despite high-dose steroids so a brain biopsy was performed which suggested a possible fungal infection. Treatment with amphotericin B resulted in prompt reversal of symptoms and radiological findings, and no further symptoms occurred during 8 years of follow-up. A diagnosis of fungal infection was not confirmed. The etiology of Susac syndrome is unknown and this anecdotal observation suggests that an infectious agent susceptible to amphotericin might have caused or triggered Susac syndrome in this patient.
- Subjects
AMPHOTERICINS; SUSAC syndrome; ENDOTHELIOMA; ARTERIAL occlusions; STEROIDS
- Publication
Acta Médica Portuguesa, 2019, Vol 32, Issue 11, p727
- ISSN
0870-399X
- Publication type
Article
- DOI
10.20344/amp.10541