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- Title
An ID card for T cells.
- Authors
Jiang, Ning; Zhang, Shuqi; Ma, Keyue
- Abstract
The article offers information on the determination of the paired T-cell antigen receptor (TCR) sequences including TCRαand TCRβ and the expression of phenotypic genes in single cells. Topics discussed include use of polymerase chain reaction (PCR) for the paired sequencing of TCR, isolation of a glycoprotein CD4 cells from the colon tissue of a patient with colorectal cancer and determination of expression of marker gene. It discusses the analysis of antigen binding in the T-cell.
- Subjects
T-cell receptor genes; POLYMERASE chain reaction; NUCLEOTIDE analysis; COLON cancer; GENE expression
- Publication
Nature Biotechnology, 2014, Vol 32, Issue 7, p639
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt.2953