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- Title
Assessment of the new nodal classification for cutaneous squamous cell carcinoma and its effect on patient stratification.
- Authors
Brunner, Markus; Ng, Beverly C.; Veness, Michael J.; Clark, Jonathan R.
- Abstract
ABSTRACT Background The American Joint Committee on Cancer (AJCC) substantially changed the staging of cutaneous squamous cell carcinoma (SCC) in the seventh edition of its staging manual. Although the system is well established in mucosal SCC, very little data are available on its prognostic value in cutaneous SCC. Methods We conducted a multivariable analysis of 672 patients with metastatic cutaneous SCC from 2 prospective cancer center databases. Results The differentiation between N1 and N2 subgroups demonstrate little prognostic importance in cutaneous SCC, whereas survival is significantly worse for N3. Conclusion Although the introduction of a unified N system for mucosal SCC and cutaneous SCC has added complexity, it does not translate into optimal distribution and stratification for metastatic cutaneous SCC. © 2014 Wiley Periodicals, Inc. Head Neck 37: 336-339, 2015
- Subjects
SQUAMOUS cell carcinoma; HEAD &; neck cancer; NOSOLOGY; METASTASIS
- Publication
Head & Neck, 2015, Vol 37, Issue 3, p336
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.23602