We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Multimodal treatment of patients with minor salivary gland cancer in the case of recurrent disease.
- Authors
Erovic, Boban M.; Schopper, Christian; Pammer, Johannes; Vormittag, Laurenz; Maleki, Amir; Brunner, Markus; Heiduschka, Gregor; Grasl, Matthaeus Ch.; Thurnher, Dietmar
- Abstract
Background Our aim in this study was to identify prognostic factors and the optimal therapeutic management in patients with minor salivary gland carcinomas. Methods Overall and disease-free survival and overall survival after recurrence in patients with adenoidcystic carcinoma (n = 25), mucoepidermoid carcinoma (n = 8), adenocarcinoma (n = 5), carcinoma ex pleomorphic adenoma (n = 4), and others (n = 5) were correlated to clinical data. Results Overall survival correlated to treatment modality (p = .039) and T classification (p = .003), whereas prolonged disease-free interval correlated to treatment (p < .001) and T classification (p = .009). Overall survival after recurrence correlated to treatment of recurrence (p = .006) and initial T classification (p = .02). Multivariate analysis showed that overall survival after recurrence correlated to treatment of recurrence (p = .019) and initial T classification (p = 0.019). T classification was a prognostic factor for overall survival (p = .002) and disease-free interval (p = .002). Conclusions The initial tumor classification is a clinical predictor for patients' overall and disease-free survival and overall survival after recurrence. Multimodal treatment significantly improves patients' overall survival. © 2010 Wiley Periodicals, Inc. Head Neck, 2010
- Subjects
SALIVARY gland cancer; COMBINED modality therapy; CANCER patients; ADENOID cystic carcinoma; ADENOCARCINOMA
- Publication
Head & Neck, 2010, Vol 32, Issue 9, p1167
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.21312