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- Title
Predictive factors for failure to identify sentinel nodes in head and neck squamous cell carcinoma.
- Authors
Hornstra, Marije T.; Alkureishi, Lee W. T.; Ross, Gary L.; Shoaib, Taimur; Soutar, David S.
- Abstract
Background The aim of this study was to ascertain which factors determine success of sentinel node biopsy (SNB). Methods We conducted a retrospective review of 121 patients with head and neck squamous cell carcinoma undergoing SNB to stage the neck. All patients underwent the triple-diagnostic procedure of preoperative lymphoscintigraphy, intraoperative blue dye, and a gamma probe. Factors contributing to failure of SNB were identified. Results SNB was unsuccessful in 12 of 121 patients (10%). Seven of the 12 patients had cT1/cT2 tumors, and 6 of these were located in the floor of mouth. SN identification was more likely to be successful in patients with cN0 necks, but this did not reach statistical significance (92% vs 84%, p = .268). Factors associated with failure included T classification (p = .01), tumor site (p = .05), and negative preoperative lymphoscintigraphy (p = .0174). Conclusion Successful sentinel lymph node harvest is related to primary tumor site, T classification, and the presence of nodes on preoperative lymphoscintigraphy. © 2008 Wiley Periodicals, Inc. Head Neck, 2008
- Subjects
MEDICAL research; SQUAMOUS cell carcinoma; LYMPH nodes; TUMORS; RADIONUCLIDE imaging; NECK tumors
- Publication
Head & Neck, 2008, Vol 30, Issue 7, p858
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.20787