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- Title
Molecular propeties of amiloride action and of its Na<sup>+</sup> transporting targets.
- Authors
Frelin, Christian; Vigne, Paul; Barbry, Pascal; Lazdunski, Michel
- Abstract
Discusses the molecular properties of amiloride action and its extrarenal effects in relation to the cardiovascular system. Mechanistic properties of the renal Na+/H+ exchange system; Structural formula for amiloride and .selected amiloride derivatives; Presence of different isotypes of the Na+/H+ exchanger with different affinities for amiloride and its derivatives in renal and non-renal tissues.
- Subjects
AMILORIDE; CARDIOVASCULAR system; SODIUM ions; HYDROGEN ions; TISSUES; KIDNEYS
- Publication
Kidney International, 1987, Vol 32, Issue 6, p785
- ISSN
0085-2538
- Publication type
Editorial
- DOI
10.1038/ki.1987.277