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- Title
Outcomes after definitive treatment for cutaneous angiosarcoma of the face and scalp.
- Authors
Guadagnolo, B. Ashleigh; Zagars, Gunar K.; Araujo, Dejka; Ravi, Vinod; Shellenberger, Thomas D.; Sturgis, Erich M.
- Abstract
Background. The aim of the present analysis was to retrospectively evaluate outcomes in patients with cutaneous angiosarcoma of the face/scalp treated curatively with surgery, radiation therapy (RT), or a combination of surgery and RT. Methods. In all, 70 patients with nonmetastatic angiosarcoma underwent surgery, RT, or combined-modality therapy. Of these, 20 patients (29%) were treated with surgery alone, 27 patients (39%) with RT alone, and 23 patients (33%) with combined-modality therapy; 44 patients received chemotherapy, either neoadjuvantly or adjuvantly or both. Results. Median follow-up was 2.1 years. The overall survival (OS) rate was 43% at 5 years, and disease-specific survival (DSS) was 46% at 5 years. Tumor size > 5 cm and satellitosis were prognostic for inferior OS and DSS. Combined- modality therapy (vs surgery alone or RT alone) was associated with improved OS, DSS, and local control. Conclusions. Primary local therapy with combined-modality therapy was associated with improved local control, OS, and DSS for patients with angiosarcoma of the face/scalp.
- Subjects
ANGIOSARCOMA; FACE cancer; SCALP; BLOOD-vessel tumors; CANCER patients; CANCER; THERAPEUTICS
- Publication
Head & Neck, 2011, Vol 33, Issue 5, p661
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.21513