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- Title
Effects of Laparoscopic Roux-en-Y Gastric Bypass on Chinese Type 2 Diabetes Mellitus Patients with Different Levels of Obesity: Outcomes After 3 Years’ Follow-Up.
- Authors
Du, Xiao; Hu, Jian-kun; Zhou, Zong-guang; Cheng, Zhong; Fu, Xiang-hui; Shi, Lei
- Abstract
Background: Laparoscopic Roux-en-Y gastric bypass (LRYGB) has been proven to be effective on treating type 2 diabetes mellitus (T2DM) in severely obese patients, but whether LRYGB surgery should be performed in obese class I patients is controversial.Materials and Methods: A retrospective study of 3-year bariatric and metabolic outcomes in different obese class T2DM patients who underwent LRYGB was conducted to compare the effectiveness of LRYGB in obese class I patients with that in obese class II/III patients in a Chinese T2DM population.Results: Totally, 58 patients with class I obesity and 45 patients with class II/III obesity were enrolled in this study. Major complications included two cases of incomplete intestinal obstructions and one anastomotic leak. The remission rates of T2DM were 70.6% in obese class I group and 77.8% in obese class II/III group at 1 year after surgery and 55.6 versus 64.3% at 3 years (all <italic>P</italic> > 0.05). Logistic regression analysis showed that higher waist circumference, lower fasting plasma glucose, and higher FCP at 2 h of OGTT were independently associated with diabetes remission at 1 year after surgery. At 1 year and thereafter, the percentage of excess weight loss was significantly greater in obese class II/III patients. At 3 years, body mass index was not significantly different between the two groups, and the obese class I patients had high recurrence rates of hypertension and hyperuricemia.Conclusions: LRYGB surgery is feasible, safe, and effective in Chinese obese class I patients with T2DM.
- Subjects
BARIATRIC surgery; LAPAROSCOPY; PEOPLE with diabetes; BODY mass index; GASTRIC bypass
- Publication
Obesity Surgery, 2018, Vol 28, Issue 3, p702
- ISSN
0960-8923
- Publication type
Article
- DOI
10.1007/s11695-017-2903-3