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- Title
Lack of change in blood pressure and arterial stiffness after high dairy intake in hyperinsulinemic subjects: a cross-over randomized controlled trial.
- Authors
Arghavani, Hana; O'Connor, Sarah; Fortier, Catherine; Rudkowska, Iwona
- Abstract
To evaluate the effects of high dairy (HD) (≥4 servings/day), compared to adequate dairy (AD) (2–3 servings/day as per Canada's Food Guide for Healthy Eating (2007)), on blood pressure (BP) and measures of arterial stiffness in hyperinsulinemic subjects. In this cross-over clinical trial, hyperinsulinemic adults were randomized to AD and HD for 6 weeks. Anthropometric, glycemic, and lipid parameters were analyzed and dietary intake was evaluated; BP, carotid-femoral pulse wave velocity, augmentation index, and measures of arterial stiffness were assessed. Twenty-seven participants completed the study. Dairy intake was 2.2 ± 1.2 servings/day during AD. In addition, lower total and low-density lipoprotein (LDL) cholesterol were observed without significant change in BP or arterial stiffness between before and after AD. During HD, the subjects consumed 5.8 ± 1.9 servings/day of dairy products, providing a higher intake of protein, saturated fat, calcium, phosphorus, sodium, and potassium compared to the baseline diet. After the HD, subjects had higher body fat, fasting insulin, homeostatic model assessment for insulin resistance (HOMA-IR) index, and triglycerides without altering BP or arterial stiffness compared to before HD. Overall, adequate or high intake of total dairy did not modify BP or arterial stiffness in hyperinsulinemic adults after 6 weeks.
- Subjects
ANALYSIS of triglycerides; BLOOD sugar analysis; LIPID analysis; BLOOD pressure; FASTING; FOOD consumption; ANTHROPOMETRY; SATURATED fatty acids; HYPERINSULINISM; LDL cholesterol; DAIRY products; ARTERIAL diseases; RANDOMIZED controlled trials; FOOD portions; PULSE wave analysis; RESEARCH funding; CROSSOVER trials; STATISTICAL sampling; NUTRITION policy; CHOLESTEROL; ADIPOSE tissues; EVALUATION
- Publication
Applied Physiology, Nutrition & Metabolism, 2024, Vol 49, Issue 3, p350
- ISSN
1715-5312
- Publication type
Article
- DOI
10.1139/apnm-2023-0053