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- Title
Wernicke's encephalopathy induced by total parental nutrition.
- Authors
T. Sequeira Lopes da Silva, J.; Almaraz Velarde, R.; Olgado Ferrero, F.; Robles Marcos, M.; Pérez Civantos, D.; M. Ramírez Moreno, J.; M. Luengo Pérez, L.
- Abstract
Wernicke's encephalopathy is an acute neurological syndrome due to thiamine deficiency, which is characterized by a typical triad of mental status changes, oculomotor dysfunction and ataxia. Despite the fact that Wernicke's encephalopathy, in developed countries, is frequently associated with chronic alcoholism, there have been a number of published cases associating this encephalopathy with parenteral feeding without vitamin supplementation. Diagnosis is primarily a clinical one, and can be supported by laboratory tests and imaging studies; treatment should start as soon as possible, for the morbidity and mortality (almost 20%) associated with this syndrome is high. Thiamine supplementation, along with other vitamins, is recommended for patients in risk of developing this syndrome.
- Subjects
WERNICKE'S encephalopathy; VITAMIN B1 deficiency; BRAIN diseases; EYE movement disorders; ATAXIA; PARENTERAL feeding
- Publication
Nutrición Hospitalaria, 2010, Vol 25, Issue 6, p1034
- ISSN
0212-1611
- Publication type
Article
- DOI
10.3305/nh.2010.25.6.4937