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- Title
Perforation of toxic megacolon in non-typhoid Salmonella enterocolitis spares young infants and is immune-mediated.
- Authors
C.-H. Chiu; L.-H. Su; C.-C. He; T.-H. Jaing; C.-C. Luo; T.-Y. Lin
- Abstract
Intestinal perforation, a life-threatening complication of toxic megacolon (TM) following non-typhoid Salmonella infection, is relatively uncommon in infants less than 1 year of age. The situation, also found in typhoid fever, appears to be cytokine-mediated. This finding may justify immunotherapy for older children with TM associated with non-typhoid Salmonella infection in order to prevent this complication.
- Subjects
MEGACOLON; COLON diseases; NEWBORN infants; SALMONELLA; IMMUNOTHERAPY
- Publication
Pediatric Surgery International, 2002, Vol 18, Issue 5/6, p410
- ISSN
0179-0358
- Publication type
Article
- DOI
10.1007/s00383-002-0830-3