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- Title
Application of Mixing Indices in Modeling Processes in Pharmaceutical Production.
- Authors
Markeev, V. B.; Blynskaya, E. V.; Tishkov, S. V.; Alekseev, K. V.; Alekseev, V. K.
- Abstract
Use of the discrete element method made it possible to make progress in modeling such a complex process as mixing. However, choosing a mixing index to evaluate the mixing efficiency of various excipients and pharmaceutical substances is a non-trivial task that makes the systematization and analysis of indices used for modeling critical. Mixing indices used in modern research on modeling the mixing process by the discrete element method starting from the Lacey index and ending with new methods applicable under fluidization conditions are discussed and analyzed.
- Subjects
MANUFACTURING processes
- Publication
Pharmaceutical Chemistry Journal, 2023, Vol 57, Issue 3, p430
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1007/s11094-023-02901-5